Last Posted: Dec-23-2016 2PM
From CDC Information Database
This database includes general CDC public health information on specific diseases and health related topics. When available, the database displays genomic information from various CDC web pages. Users are also encouraged to conduct searches of CDC website for additional information.
- Breast Cancer in Young Women
- Breast and Ovarian Cancer
- Breast Cancer Awareness
- Bring Your Brave Campaign
- Does Breast or Ovarian Cancer Run in Your Family?
- Does Breast or Ovarian Cancer Run in Your Family?
From NIH National Cancer Institute Web Sites
From CDC-Authored Genomics Publication Database
This database contains CDC-authored publications in public health genomics including infectious diseases, newborn screening, reproductive health, genetic testing, cancer, chronic diseases, birth defects and developmental disabilities, environmental and occupational health as well as laboratory, bioinformatics and statistical methods.
- Patterns and Trends in Age-Specific Black-White Differences in Breast Cancer Incidence and Mortality - United States, 1999-2014.
Richardson Lisa C et al. MMWR. Morbidity and mortality weekly report 2016 Oct 65(40) 1093-1098 - What Predicts an Advanced-Stage Diagnosis of Breast Cancer? Sorting Out the Influence of Method of Detection, Access to Care, and Biologic Factors.
Lipscomb Joseph et al. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2016 Jan - Reduced risk of breast cancer associated with recreational physical activity varies by HER2 status.
Ma Huiyan et al. Cancer Med 2015 Jul 4(7) 1122-35 - Annual Report to the Nation on the Status of Cancer, 1975-2011, Featuring Incidence of Breast Cancer Subtypes by Race/Ethnicity, Poverty, and State.
Kohler Betsy A et al. J. Natl. Cancer Inst. 2015 Jun 107(6) djv048 - Clinical utility of gene-expression profiling in women with early breast cancer: an overview of systematic reviews.
Marrone Michael et al. Genet. Med. 2015 Jul 2. 17(7) 519-32
From Implementation Database
This database focuses on state and national activities that integrate genomics into public health programs and clinical practice
- BRCA Patient - Spanish version 2016
[Disease: Breast Cancer|Ovarian Cancer; Type: Education; State: Multiple States] - http://www.mdedge.com/jcso/article/110048/gynecologic-cancer/hereditary-breast-and-ovarian-cancer-risk-assessment-minority
[Disease: Breast Cancer|Ovarian Cancer; Type: Data|Program; State: Georgia] - Implementing a screening tool for identifying patients at risk for hereditary breast and ovarian cancer: a statewide initiative.
[Disease: Ovarian Cancer|Breast Cancer; Type: Data|Program; State: Georgia] - Implementing Public Health Genomics in Your State: Resources from the CDC Office of Public Health Genomics
[Disease: Lynch syndrome|Breast Cancer|Ovarian Cancer; Type: Education; State: Multiple States] - JAX Genomic Education : Genetic Testing for Breast Cancer Risk
[Disease: Breast Cancer; Type: Education; State: Multiple States]
From Guideline Database
This database contains updated guidelines, policies and recommendations on genomic research and practice, as provided by professional organizations, federal advisory groups, expert panels and policy groups.
- Role of Patient and Disease Factors in Adjuvant Systemic Therapy Decision Making for Early-Stage, Operable Breast Cancer: American Society of Clinical Oncology Endorsement of Cancer Care Ontario Guideline Recommendations.
Published 2016 (American Society of Clinical Oncology) - Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers.
Published 2015 - Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline.
Published 2016 (American Society of Clinical Oncology) - Screening for Breast Cancer: U.S. Preventive Services Task Force Recommendation Statement.
Published 2016 (U.S. Preventive Services Task Force) - Recommendations from the EGAPP Working Group: does the use of Oncotype DX tumor gene expression profiling to guide treatment decisions improve outcomes in patients with breast cancer?
Published 2015 (Evaluation of Genomic Applications in Practice and Prevention)
From Tier Table Database
CDC Office of Public Health Genomics (OPHG) conducts horizon scanning (a systematic research method to find and follow novel technologies appearing in the literature) to identify and track the progress of genomic tests as they move from research into clinical and public health practice. As an aid in organizing horizon scanning results, OPHG ranks genomic tests, and family health history applications, by levels of evidence. See detail.
| Disease/Disorder | Test to be Assessed | Intended Use | Tier Classified | Detail |
|---|---|---|---|---|
| Dukes’ C colon cancer, metastatic colorectal cancer, metastatic breast cancer | DPD testing | Pharmacogenomic for 5-FU (capecitabine) | Tier 2  | |
| Risk for primary breast cancer or breast cancer recurrence | CYP2D6 | Pharmacogenomic - informing therapeutic choice, tamoxifen | Tier 2 | |
| Invasive breast cancer and breast cancer | ER-alpha and PgR status | Pharmacogenomic: for ER-alpha (ESR1)-modulating agents, recurrence risk, prognostic | Tier 2 | |
| Breast cancer | Gene expression profiles | Recurrence: risk prediction; prognostic | Tier 2 | |
| Breast cancer (ER+/LN-/HER2-), intermediate risk of recurrence | Oncotype DX® | prognostic; guiding decision-making: adjuvant chemotherapy | Tier 1 |
From HuGE Literature Finder Database
This database contains published literature on genetic associations and other human genome epidemiology
- Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.
Journal of the National Cancer Institute 2017 Jan 109 (1): .
Kotsopoulos Joanne, Huzarski Tomasz, Gronwald Jacek, Singer Christian F, Moller Pal, Lynch Henry T, Armel Susan, Karlan Beth, Foulkes William D, Neuhausen Susan L, Senter Leigha, Tung Nadine, Weitzel Jeffrey N, Eisen Andrea, Metcalfe Kelly, Eng Charis, Pal Tuya, Evans Gareth, Sun Ping, Lubinski Jan, Narod Steven A, - AQP5 Variants Affect Tumoral Expression of AQP5 and Survival in Patients with Early Breast Cancer.
Oncology 2016 Dec .
Lee Soo Jung, Kang Byung Woog, Kim Jong Gwang, Jung Jin Hyang, Lee Jeeyeon, Kim Wan Wook, Park Ho Yong, Jeong Jae-Hwan, Jeong Ji Yun, Park Ji-Young, Park Jae Hyung, Chae Yee S - Association between FGFR2 (rs2981582, rs2420946 and rs2981578) polymorphism and breast cancer susceptibility: a meta-analysis.
Oncotarget 2016 Dec .
Zhang Yafei, Zeng Xianling, Liu Pengdi, Hong Ruofeng, Lu Hongwei, Ji Hong, Lu Le, Li Yimi - rs15869 at miRNA binding site in BRCA2 is associated with breast cancer susceptibility.
Medical oncology (Northwood, London, England) 2016 Dec 33 (12): 135.
Cao Jingjing, Luo Chenglin, Yan Rui, Peng Rui, Wang Kaijuan, Wang Peng, Ye Hua, Song Chunh - The role of base excision repair in pathogenesis of breast cancer in the Polish population.
Molecular carcinogenesis 2016 Dec 55 (12): 1899-1914.
Cuchra Magda, Mucha Bartosz, Markiewicz Lukasz, Przybylowska-Sygut Karolina, Pytel Dariusz, Jeziorski Arkadiusz, Kordek Radzis?aw, Majsterek Ireneu
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