BRCA MUTATIONS

PubMed Clinical Queries



From PubMed Clinical Queries

PubMed Clinical Queries is an utility offered by PubMed to search scientific literature in specific clinical research areas

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• Search PubMed Clinical Queries for "Brca" 

Results: 5 of 828

• PARP inhibitors in platinum-sensitive high-grade serous ovarian cancer.
  Morgan RD, Clamp AR, Evans DGR, Edmondson RJ, Jayson GC.Cancer Chemother Pharmacol. 2018 Feb 20; . Epub 2018 Feb 20.
• Clinical Outcome of Prostate Cancer Patients with Germline DNA Repair Mutations: Retrospective Analysis from an International Study.
  Mateo J, Cheng HH, Beltran H, Dolling D, Xu W, Pritchard CC, Mossop H, Rescigno P, Perez-Lopez R, Sailer V, et al.Eur Urol. 2018 Jan 29; . Epub 2018 Jan 29.
• Prexasertib, a cell cycle checkpoint kinase 1 and 2 inhibitor, in BRCA wild-type recurrent high-grade serous ovarian cancer: a first-in-class proof-of-concept phase 2 study.
  Lee JM, Nair J, Zimmer A, Lipkowitz S, Annunziata CM, Merino MJ, Swisher EM, Harrell MI, Trepel JB, Lee MJ, et al.Lancet Oncol. 2018 Feb; 19(2):207-215. Epub 2018 Jan 18.
• Phase 1 trial evaluating cisplatin, gemcitabine, and veliparib in 2 patient cohorts: Germline BRCA mutation carriers and wild-type BRCA pancreatic ductal adenocarcinoma.
  O'Reilly EM, Lee JW, Lowery MA, Capanu M, Stadler ZK, Moore MJ, Dhani N, Kindler HL, Estrella H, Maynard H, et al.Cancer. 2018 Jan 16; . Epub 2018 Jan 16.
• Impact of homologous recombination deficiency biomarkers on outcomes in patients with triple-negative breast cancer treated with doxorubicin-based adjuvant chemotherapy (SWOG S9313).
  Sharma P, Barlow WE, Godwin AK, Pathak H, Isakova K, Williams D, Timms KM, Hartman AR, Wenstrup RJ, Linden HM, et al.Ann Oncol. 2017 Dec 23; . Epub 2017 Dec 23.

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This column displays citations filtered to a specific clinical study category and scope. These search filters were developed by Haynes RB et al. See more filter information.

Systematic Reviews

Results: 5 of 138

• Hereditary Cancers in Gynecology: What Physicians Should Know About Genetic Testing, Screening, and Risk Reduction.
  Ring KL, Modesitt SC.Obstet Gynecol Clin North Am. 2018 Mar; 45(1):155-173.
• Cost-effectiveness and comparative effectiveness of cancer risk management strategies in BRCA1/2 mutation carriers: a systematic review.
  Petelin L, Trainer AH, Mitchell G, Liew D, James PA.Genet Med. 2018 Jan 11; . Epub 2018 Jan 11.
• Genetic Tests for Breast and Ovarian Cancer
  Juvet LK, Natvig Norderhaug I.2008 Feb.
• Variability in the therapeutic management of advanced ovarian cancer patients: a five-country survey of oncologists.
  Audibert C, Perlaky A, Stuntz M, Glass D.Drug Des Devel Ther. 2017; 11:3471-3479. Epub 2017 Dec 6.
• A comprehensive genomic meta-analysis identifies confirmatory role of <i>OBSCN</i> gene in breast tumorigenesis.
  Rajendran BK, Deng CX.Oncotarget. 2017 Nov 24; 8(60):102263-102276. Epub 2017 Aug 23.

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This column displays citations for systematic reviews, meta-analyses, reviews of clinical trials, evidence-based medicine, consensus development conferences, and guidelines. See filter information or additional related sources.

Medical Genetics

Topic:AllDiagnosisDifferential DiagnosisClinical DescriptionManagementGenetic CounselingMolecular GeneticsGenetic Testing

Results: 5 of 2797

• Paternal lineage early onset hereditary ovarian cancers: A Familial Ovarian Cancer Registry study.
  Eng KH, Szender JB, Etter JL, Kaur J, Poblete S, Huang RY, Zhu Q, Grzesik KA, Battaglia S, Cannioto R, et al.PLoS Genet. 2018 Feb; 14(2):e1007194. Epub 2018 Feb 15.
• Male BRCA mutation carriers: clinical characteristics and cancer spectrum.
  Ibrahim M, Yadav S, Ogunleye F, Zakalik D.BMC Cancer. 2018 Feb 13; 18(1):179. Epub 2018 Feb 13.
• An iPhone Application Intervention to Promote Surveillance Among Women with a BRCA Mutation: Pre-intervention Data.
  Cohen SA, Scherr CL, Nixon DM.J Genet Couns. 2018 Feb 10; . Epub 2018 Feb 10.
• A Two-Phase Approach to Developing SNAP: an iPhone Application to Support Appointment Scheduling and Management for Women with a BRCA Mutation.
  Scherr CL, Feuston JL, Nixon DM, Cohen SA.J Genet Couns. 2018 Feb 8; . Epub 2018 Feb 8.
• Bone loss in women with BRCA1 and BRCA2 mutations.
  Powell CB, Alabaster A, Stoller N, Armstrong MA, Salyer C, Hamilton I, Raine-Bennett T.Gynecol Oncol. 2018 Feb 5; . Epub 2018 Feb 5.

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This column displays citations pertaining to topics in medical genetics. See more filter information.