BRCA MUTATIONS

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From PubMed Clinical Queries

PubMed Clinical Queries is an utility offered by PubMed to search scientific literature in specific clinical research areas

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• Search PubMed Clinical Queries for "Brca" 

Results: 5 of 843

• Development of a Web-based Family Intervention for BRCA Carriers and Their Biological Relatives: Acceptability, Feasibility, and Usability Study.
  Katapodi MC, Jung M, Schafenacker AM, Milliron KJ, Mendelsohn-Victor KE, Merajver SD, Northouse LL.JMIR Cancer. 2018 Apr 13; 4(1):e7. Epub 2018 Apr 13.
• Ovarian Cancer Prevention and Screening.
  Menon U, Karpinskyj C, Gentry-Maharaj A.Obstet Gynecol. 2018 Apr 6; . Epub 2018 Apr 6.
• Olaparib for the treatment of breast cancer.
  Griguolo G, Dieci MV, Guarneri V, Conte P.Expert Rev Anticancer Ther. 2018 Mar 30; :1-12. Epub 2018 Mar 30.
• Addition of the PARP inhibitor veliparib plus carboplatin or carboplatin alone to standard neoadjuvant chemotherapy in triple-negative breast cancer (BrighTNess): a randomised, phase 3 trial.
  Loibl S, O'Shaughnessy J, Untch M, Sikov WM, Rugo HS, McKee MD, Huober J, Golshan M, von Minckwitz G, Maag D, et al.Lancet Oncol. 2018 Apr; 19(4):497-509. Epub 2018 Feb 28.
• PARP inhibitors in platinum-sensitive high-grade serous ovarian cancer.
  Morgan RD, Clamp AR, Evans DGR, Edmondson RJ, Jayson GC.Cancer Chemother Pharmacol. 2018 Apr; 81(4):647-658. Epub 2018 Feb 20.

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This column displays citations filtered to a specific clinical study category and scope. These search filters were developed by Haynes RB et al. See more filter information.

Systematic Reviews

Results: 5 of 138

• Hereditary Cancers in Gynecology: What Physicians Should Know About Genetic Testing, Screening, and Risk Reduction.
  Ring KL, Modesitt SC.Obstet Gynecol Clin North Am. 2018 Mar; 45(1):155-173.
• Cost-effectiveness and comparative effectiveness of cancer risk management strategies in BRCA1/2 mutation carriers: a systematic review.
  Petelin L, Trainer AH, Mitchell G, Liew D, James PA.Genet Med. 2018 Jan 11; . Epub 2018 Jan 11.
• Genetic Tests for Breast and Ovarian Cancer
  Juvet LK, Natvig Norderhaug I.2008 Feb.
• Variability in the therapeutic management of advanced ovarian cancer patients: a five-country survey of oncologists.
  Audibert C, Perlaky A, Stuntz M, Glass D.Drug Des Devel Ther. 2017; 11:3471-3479. Epub 2017 Dec 6.
• A comprehensive genomic meta-analysis identifies confirmatory role of <i>OBSCN</i> gene in breast tumorigenesis.
  Rajendran BK, Deng CX.Oncotarget. 2017 Nov 24; 8(60):102263-102276. Epub 2017 Aug 23.

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This column displays citations for systematic reviews, meta-analyses, reviews of clinical trials, evidence-based medicine, consensus development conferences, and guidelines. See filter information or additional related sources.

Medical Genetics

Topic:AllDiagnosisDifferential DiagnosisClinical DescriptionManagementGenetic CounselingMolecular GeneticsGenetic Testing

Results: 5 of 2865

• FDA Approval Summary: Niraparib for the maintenance treatment of patients with recurrent ovarian cancer in response to platinum-based chemotherapy.
  Ison G, Howie LJ, Amiri-Kordestani L, Zhang L, Tang S, Sridhara R, Pierre V, Charlab R, Ramamoorthy A, Song P, et al.Clin Cancer Res. 2018 Apr 12; . Epub 2018 Apr 12.
• Maternal perceptions of BRCA genetic counseling communication processes about disclosing cancer risk information to children and adult relatives.
  Hamilton JG, Peshkin BN, Mays D, DeMarco TA, Patenaude AF, Tercyak KP.Psychooncology. 2018 Apr 12; . Epub 2018 Apr 12.
• Support needs of couples with hereditary breast and ovarian cancer during reproductive decision-making.
  Gietel-Habets JJG, de Die-Smulders CEM, Derks-Smeets IAP, Tibben A, Tjan-Heijnen VCG, van Golde R, Gomez-Garcia E, van Osch LADM.Psychooncology. 2018 Apr 12; . Epub 2018 Apr 12.
• RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA mutated breast cancer.
  Cruz C, Castroviejo-Bermejo M, Gutiérrez-Enríquez S, Llop-Guevara A, Ibrahim YH, Gris-Oliver A, Bonache S, Morancho B, Bruna A, Rueda OM, et al.Ann Oncol. 2018 Apr 4; . Epub 2018 Apr 4.
• Current detection rates and time-to-detection of all identifiable <i>BRCA</i> carriers in the Greater London population.
  Manchanda R, Blyuss O, Gaba F, Gordeev VS, Jacobs C, Burnell M, Gan C, Taylor R, Turnbull C, Legood R, et al.J Med Genet. 2018 Apr 5; . Epub 2018 Apr 5.

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This column displays citations pertaining to topics in medical genetics. See more filter information.