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From PubMed Clinical Queries

PubMed Clinical Queries is an utility offered by PubMed to search scientific literature in specific clinical research areas

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• Search PubMed Clinical Queries for "Brca" 

Results: 5 of 890

• Quality of life in patients with recurrent ovarian cancer treated with niraparib versus placebo (ENGOT-OV16/NOVA): results from a double-blind, phase 3, randomised controlled trial.
  Oza AM, Matulonis UA, Malander S, Hudgens S, Sehouli J, Del Campo JM, Berton-Rigaud D, Banerjee S, Scambia G, Berek JS, et al.Lancet Oncol. 2018 Jul 16; . Epub 2018 Jul 16.
• Clinical outcomes of adolescents and young adults with advanced solid tumours participating in phase I trials.
  Sundar R, McVeigh T, Dolling D, Petruckevitch A, Diamantis N, Ang JE, Chenard-Poiriér M, Collins D, Lim J, Ameratunga M, et al.Eur J Cancer. 2018 Jul 16; 101:55-61. Epub 2018 Jul 16.
• Description of Genetic Variants in <i>BRCA</i> Genes in Mexican Patients with Ovarian Cancer: A First Step towards Implementing Personalized Medicine.
  Delgado-Balderas JR, Garza-Rodriguez ML, Gomez-Macias GS, Barboza-Quintana A, Barboza-Quintana O, Cerda-Flores RM, Miranda-Maldonado I, Vazquez-Garcia HM, Valdez-Chapa LD, Antonio-Macedo M, et al.Genes (Basel). 2018 Jul 11; 9(7). Epub 2018 Jul 11.
• Single-agent PARP inhibitors for the treatment of patients with <i>BRCA</i>-mutated HER2-negative metastatic breast cancer: a systematic review and meta-analysis.
  Poggio F, Bruzzone M, Ceppi M, Conte B, Martel S, Maurer C, Tagliamento M, Viglietti G, Del Mastro L, de Azambuja E, et al.ESMO Open. 2018; 3(4):e000361. Epub 2018 Jun 20.
• Change in inflammatory biomarkers and adipose tissue in BRCA1/2+ breast cancer survivors following a year-long lifestyle modification program.
  Sturgeon KM, Foo WY, Heroux ML, Schmitz K.Cancer Prev Res (Phila). 2018 Jun 20; . Epub 2018 Jun 20.

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This column displays citations filtered to a specific clinical study category and scope. These search filters were developed by Haynes RB et al. See more filter information.

Systematic Reviews

Results: 5 of 148

• Prophylactic mastectomy versus surveillance for the prevention of breast cancer in women's BRCA carriers.
  Honold F, Camus M.Medwave. 2018 Jul 9; 18(4):e7161. Epub 2018 Jul 9.
• Single-agent PARP inhibitors for the treatment of patients with <i>BRCA</i>-mutated HER2-negative metastatic breast cancer: a systematic review and meta-analysis.
  Poggio F, Bruzzone M, Ceppi M, Conte B, Martel S, Maurer C, Tagliamento M, Viglietti G, Del Mastro L, de Azambuja E, et al.ESMO Open. 2018; 3(4):e000361. Epub 2018 Jun 20.
• Niraparib for the treatment of ovarian cancer.
  Essel KG, Moore KN.Expert Rev Anticancer Ther. 2018 Aug; 18(8):727-733. Epub 2018 Jul 2.
• A systematic review on the frequency of BRCA promoter methylation in breast and ovarian carcinomas of BRCA germline mutation carriers: Mutually exclusive, or not?
  Vos S, van Diest PJ, Moelans CB.Crit Rev Oncol Hematol. 2018 Jul; 127:29-41. Epub 2018 May 14.
• Platinum-based neoadjuvant chemotherapy in triple-negative breast cancer: a systematic review and meta-analysis.
  Poggio F, Bruzzone M, Ceppi M, Pondé NF, La Valle G, Del Mastro L, de Azambuja E, Lambertini M.Ann Oncol. 2018 Jul 1; 29(7):1497-1508.

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This column displays citations for systematic reviews, meta-analyses, reviews of clinical trials, evidence-based medicine, consensus development conferences, and guidelines. See filter information or additional related sources.

Medical Genetics

Topic:AllDiagnosisDifferential DiagnosisClinical DescriptionManagementGenetic CounselingMolecular GeneticsGenetic Testing

Results: 5 of 2947

• Men's and Women's Approaches to Disclosure About BRCA-Related Cancer Risks and Family Planning Decision-Making.
  Dean M, Rauscher EA.Qual Health Res. 2018 Jul 27; :1049732318788377. Epub 2018 Jul 27.
• Evolution of genetic assessment for BRCA-associated gynaecologic malignancies: a Canadian multisociety roadmap.
  McCuaig JM, Stockley TL, Shaw P, Fung-Kee-Fung M, Altman AD, Bentley J, Bernardini MQ, Cormier B, Hirte H, Kieser K, et al.J Med Genet. 2018 Jul 24; . Epub 2018 Jul 24.
• Quality of life in patients with recurrent ovarian cancer treated with niraparib versus placebo (ENGOT-OV16/NOVA): results from a double-blind, phase 3, randomised controlled trial.
  Oza AM, Matulonis UA, Malander S, Hudgens S, Sehouli J, Del Campo JM, Berton-Rigaud D, Banerjee S, Scambia G, Berek JS, et al.Lancet Oncol. 2018 Jul 16; . Epub 2018 Jul 16.
• The yield of full BRCA1/2 genotyping in Israeli high-risk breast/ovarian cancer patients who do not carry the predominant mutations.
  Barnes-Kedar I, Bernstein-Molho R, Ginzach N, Hartmajer S, Shapira T, Magal N, Kalis ML, Peretz T, Shohat M, Basel-Salmon L, et al.Breast Cancer Res Treat. 2018 Jul 16; . Epub 2018 Jul 16.
• Breast Cancer Genetics and Indications for Prophylactic Mastectomy.
  Krontiras H, Farmer M, Whatley J.Surg Clin North Am. 2018 Aug; 98(4):677-685. Epub 2018 May 30.

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This column displays citations pertaining to topics in medical genetics. See more filter information.