sábado, 1 de diciembre de 2018

Cystic Fibrosis News Today Weekly Digest


Cystic Fibrosis Weekly Update

Contents:

European Union Expands Kalydeco’s Approval to Certain CF Patients Ages 1-2

Nov 30, 2018 07:00 am | Patricia Inacio, PhD



KalydecoKalydeco (ivacaftor) by Vertex Pharmaceuticals has been approved in the European Union for children ages 1-2 with cystic fibrosis (CF) who carry at least one of nine mutations in the CFTR gene — G551D, G1244E, G1349D, G178R, G551S, S1251N, S1255P, S549N, or S549R — that prevent the CFTR chloride channel from working properly. “For the first time, EU physicians can now treat the underlying cause of CF earlier than ever, […]
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Triple Combo with VX-659 Improves Lung Function in CF Patients with F508del Mutation, Phase 3 Trials Show

Nov 29, 2018 07:00 am | Jose Marques Lopes, PhD



VX-659, Phase 3 trialsTreatment with a triple combination — the new CFTR corrector VX-659, together with tezacaftor and Kalydeco (ivacaftor) — significantly improved lung function and was well-tolerated by cystic fibrosis (CF) patients, ages 12 and older, with at least one F508del mutation in two Phase 3 studies, according to Vertex Pharmaceuticals. This data support a potential request for approval of this triple […]
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As Both Patient and Scientist, I’m Putting Nature’s Medicine to the Test

Nov 28, 2018 03:00 pm | Ella Balasa



I peered into one of the incubators that stored my petri dishes for 24 hours, anxious to see whether I would discover discoloration and unevenness on the surface, which would have indicated that my experiment produced favorable results. I wanted to see a visual representation of whether manuka honey kills the stubborn Pseudomonas bacterium, which dwells […]
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