Activation of TGR5 protects blood brain barrier via the BRCA1/Sirt1 pathway after middle cerebral artery occlusion in rats | Journal of Biomedical Science | Full Text

Activation of TGR5 protects blood brain barrier via the BRCA1/Sirt1 pathway after middle cerebral artery occlusion in rats | Journal of Biomedical Science | Full Text

Activation of TGR5 protects blood brain barrier via the BRCA1/Sirt1 pathway after middle cerebral artery occlusion in rats

The disruption of the blood–brain barrier (BBB) plays a critical event in the pathogenesis of ischemia stroke. TGR5 is recognized as a potential target for the treatment for neurologic disorders.

Authors:Hui Liang, Nate Matei, Devin W. McBride, Yang Xu, Jiping Tang, Benyan Luo and John H. Zhang

Citation:Journal of Biomedical Science 2020 27:61

Content type:Research

Published on: 8 May 2020

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