TELOMERES UPDATE June 23-30, 2016 ▲ Public Health Genomics Knowledge Base (v1.0)

Public Health Genomics Knowledge Base (v1.0)



June 23-30, 2016

TELOMERES

Last Updated: Jun 23, 2016

• Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies
  M Jafri et al, Genome Medicine, June 20, 2016
• Telomere-associated aging disorders.
  Opresko Patricia L et al. Ageing research reviews 2016 May
• Telomere and Telomerase Therapeutics in Cancer.
  Xu Yucheng et al. Genes 2016 (6)
• Short Telomere Length and Ischemic Heart Disease: Observational and Genetic Studies in 290 022 Individuals.
  Scheller Madrid Alexander, et al. Clinical chemistry 2016 6
• Danazol Treatment for Telomere Diseases
  DM Townsley et al, NEJM, May 18, 2016
• Increase of Telomere Length by a Sex Hormone
  NEJM Video, May 18, 2016
• Arsenic exposure, genetic susceptibility and leukocyte telomere length in an Italian young adult population.
  Borghini Andrea, et al. Mutagenesis 2016 4
• Association of telomere length with IL-6 levels during an obesity treatment in adolescents: interaction with the-174G/C polymorphism in the IL-6gene.
  García-Calzón S, et al. Pediatric obesity 2016 4
• Differences in telomere length between sporadic and familial cutaneous melanoma.
  Menin C, et al. The British journal of dermatology 2016 4
• Polymorphisms in human telomerase reverse transcriptase (hTERT) gene and susceptibility to gastric cancer in a Turkish population: Hospital-based case-control study.
  Bayram Süleyman, et al. Gene 2016 3
• Increased MTHFR promoter methylation in mothers of Down syndrome individuals.
  Coppedè Fabio, et al. Mutation research 2016 2 1-6
• Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12.
  Mäkinen Netta, et al. PLoS genetics 2016 2 (2) e1005850
• Acquired TERT promoter mutations stimulate TERT transcription in mantle cell lymphoma.
  Panero Julieta, et al. American journal of hematology 2016 2
• Quantitative trait association study for mean telomere length in the South Asian Genomes.
  Anna Hakobyan, et al. Bioinformatics (Oxford, England) 2016 1
• Epidemiological and Mendelian randomisation studies of dihydrotestosterone and estradiol, and leucocyte telomere length in men.
  Yeap Bu B, et al. The Journal of clinical endocrinology and metabolism 2016 1 jc20154139
• [Detection of subtelomeric copy number variations in children with intellectual disability].
  Zhu Li-Na, et al. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 2015 12 (12) 1273-6
• Assessment of the clinical relevance of 17q25.3 copy number and three-dimensional telomere organization in non-small lung cancer patients.
  Sunpaweravong Patrapim, et al. Journal of cancer research and clinical oncology 2015 11
• U-shaped association between telomere length and esophageal squamous cell carcinoma risk: a case-control study in Chinese population.
  Du Jiangbo, et al. Frontiers of medicine 2015 11
• Analysis of association among clinical features and shorter leukocyte telomere length in mitochondrial diabetes with m.3243A>G mitochondrial DNA mutation.
  Zhou Mei-Cen, et al. BMC medical genetics 2015 0 (1) 92
• TERT Polymorphism rs2853669 Influences on Lung Cancer Risk in the Korean Population.
  Yoo Seung Soo, et al. Journal of Korean medical science 2015 10 (10) 1423-8
• Association of leukocyte telomere length in peripheral blood leukocytes with endometrial cancer risk in Caucasian Americans.
  Sun Yuhui, et al. Carcinogenesis 2015 9
• Genetic and epigenetic trends in telomere research: a novel way in immunoepigenetics.
  Melicher Dora et al. Cell. Mol. Life Sci. 2015 Jul 20.
• Is childhood stress associated with shorter telomeres?
  Næss Ane Brandtzæg et al. Tidsskr. Nor. Laegeforen. 2015 Aug (15) 1356-1360
• Questioning causal involvement of telomeres in aging.
  Simons Mirre J P et al. Ageing Res. Rev. 2015 Aug 21.
• Association between TERT promoter polymorphisms and acute myeloid leukemia risk and prognosis.
  Mosrati Mohamed Ali, et al. Oncotarget 2015 7
• Increased frequencies of the killer immunoglobulin-like receptor genes KIR2DL2 and KIR2DS2 are associated with neuroblastoma.
  Keating S E, et al. Tissue antigens 2015 9 (3) 172-7
• Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study.
  Bressler Jan, et al. BMC medical genetics 2015 0 (1) 52
• A pathway approach to evaluating the association between the CHIEF pathway and risk of colorectal cancer.
  Slattery Martha L, et al. Carcinogenesis 2015 1 (1) 49-59
• Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors.
  Mangerel Joshua, et al. Acta neuropathologica 2014 12 (6) 853-62
• Automated Assay of Telomere Length Measurement and Informatics for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort.
  Lapham Kyle, et al. Genetics 2015 8 (4) 1061-72

• CDC Information (1)
• CDC-Authored Pub (3)

• Human (11)
• Pathogen (0)

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• Human (2)
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Relevant Resources

• Cancer Genomics and Epidemiology Navigator (CGEN)
• Genetics and Genomics Competencies Center (G2C2)
• NIH Genetic Testing Registry
• NIH MedGen Database
• Online Mendelian Inheritance in Man (OMIM)
• PharmGKB

Public Health Genomics Knowledge Base (v1.0)