Researchers report a liquid biopsy for COVID-19
A new study published on the preprint server medRxiv* in July 2020 reports the potential of cell-free DNA as a marker of the severity of disease in COVID-19. This could help triage patients as well as provide a prognostic marker.
The current COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has become a significant public health crisis around the world. It is a multisystemic illness, though it appears to be most recognizable as severe pneumonia leading to acute respiratory distress syndrome (ARDS) in a significant minority of cases.
The fact remains that the infection is asymptomatic and, therefore, unrecognizable in most cases, allowing its extensive and rapid spread. There is a great need to identify biomarkers capable of predicting the severity of the disease early on, so as to help manage such patients appropriately. Moreover, the mechanism of disease is also far from clear.
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