Addiction ► Public Health Genomics Knowledge Base (v1.0)

Public Health Genomics Knowledge Base (v1.0)










Last Updated: Apr 27, 2016

• Role of CYP2C19 gene polymorphism in acute alcohol withdrawal treatment with loading dose of diazepam in a South Indian population.
  Jose Manu, et al. European journal of clinical pharmacology 2016 4
• Nicotine-specific and non-specific effects of cigarette smoking on endogenous opioid mechanisms.
  Nuechterlein Emily B, et al. Progress in neuro-psychopharmacology & biological psychiatry 2016 4
• Mouse and Human Genetic Analyses Associate Kalirin with Ventral Striatal Activation during Impulsivity and with Alcohol Misuse.
  Peña-Oliver Yolanda, et al. Frontiers in genetics 2016 0 52
• Association study of GABA system genes polymorphisms with amphetamine-induced psychotic disorder in a Han Chinese population.
  Zhang Kai, et al. Neuroscience letters 2016 4
• ADHD risk alleles associated with opiate addiction: study of addicted parents and their children.
  Ornoy Asher, et al. Pediatric research 2016 4
• The ABCB1, rs9282564, AG and TT Genotypes and the COMT, rs4680, AA Genotype are less frequent in Deceased Patients with Opioid Addiction (DOA) than in Living Patients with Opioid Addiction (LOA).
  Christoffersen Dorte J, et al. Basic & clinical pharmacology & toxicology 2016 4
• Association of Common Polymorphisms in the Nicotinic Acetylcholine Receptor Alpha4 Subunit Gene with an Electrophysiological Endophenotype in a Large Population-Based Sample.
  Mobascher A, et al. PloS one 2016 0 (4) e0152984
• A prospective study of genetic factors, human laboratory phenotypes, and heavy drinking in late adolescence.
  Hendershot Christian S, et al. Addiction biology 2016 4
• TPH1 and 5-HTTLPR Genes Specifically Interact in Opiate Dependence but Not in Alcohol Dependence.
  Wang Tzu-Yun, et al. European addiction research 2016 4 (4) 201-209
• "Weak" opioid analgesics. Codeine, dihydrocodeine and tramadol: no less risky than morphine.
  Prescrire international 2016 2 (168) 45-50
• Genetic imaging consortium for addiction medicine: From neuroimaging to genes.
  Mackey Scott et al. Progress in brain research 2016 203-23
• Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks.
  Sherva Richard, et al. JAMA psychiatry 2016 3
• Gene by Environment Interaction Linking the Chromosome 15q25 Locus With Cigarette Consumption and Lung Cancer Susceptibility - Are African American Affected Differently?
  Hopkins R J, et al. EBioMedicine 2016 2 13-4
• A meta-analysis of the relationship between brain dopamine receptors and obesity: a matter of changes in behavior rather than food addiction?
  Benton D, et al. International journal of obesity (2005) 2016 3 S12-21
• What does addiction medicine expect from neuroscience? From genes and neurons to treatment responses.
  Le Foll Bernard et al. Progress in brain research 2016 419-47
• Smokescreen: a targeted genotyping array for addiction research.
  Baurley James W, et al. BMC genomics 2016 0 (1) 145
• X Chromosome Inactivation in Opioid Addicted Women.
  Vousooghi Nasim, et al. Basic and clinical neuroscience 2015 7 (3) 179-84
• Meta-analysis of the association between a serotonin transporter 5-HTTLPR polymorphism and smoking cessation.
  Choi Hye D, et al. Psychiatric genetics 2016 4 (2) 87-91
• Cannabis use and symptoms of anxiety in adolescence and the moderating effect of the serotonin transporter gene.
  Otten Roy, et al. Addiction biology 2016 2
• Epigenetics and Addiction.
  Cadet Jean Lud et al. Clinical pharmacology and therapeutics 2016 Feb
• Born to do drugs: overcoming a family history of addiction 
  Drug Rehab
• RNA-binding proteins, neural development and the addictions.
  Bryant C D et al. Genes, brain, and behavior 2016 Jan (1) 169-86
• Temperament and Externalizing Behavior as Mediators of Genetic Risk on Adolescent Substance Use.
  Trucco Elisa M, et al. Journal of abnormal psychology 2016 2
• Neurobiologic Advances from the Brain Disease Model of Addiction
  ND Volkov, NEJM January 27, 2016
• Adding Genetic Testing to Evidence-Based Guidelines to Determine the Safest and Most Effective Chronic Pain Treatment for Injured Workers.
  Meshkin Brian et al. International journal of biomedical science : IJBS 2015 Dec 11(4) 157-65
• Association of N-Methyl-D-Aspartate Receptor 2B Subunit (GRIN2B) polymorphism with earlier age at onset of withdrawal symptoms in Indian alcohol dependent subjects.
  Paul Pradip, et al. Journal of addictive diseases 2016 1 0
• [Association between genotype and allele frequencies of CYP2A6*12 and rs16969968 in CHRNA5 variants with smoking and body mass index in young subjects from Northeast Mexico].
  Borrego-Soto Gissela, et al. Revista me?dica de Chile 2015 11 (11) 1377-85
• Longitudinal predictors of cannabis use and dependence in offspring from families at ultra high risk for alcohol dependence and in control families.
  Hill Shirley Y, et al. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2016 1
• GABBR1 and SLC6A1, Two Genes Involved in Modulation of GABA Synaptic Transmission, Influence Risk for Alcoholism: Results from Three Ethnically Diverse Populations.
  Enoch Mary-Anne, et al. Alcoholism, clinical and experimental research 2016 1 (1) 93-101
• Limited Evidence for Association of Genome-Wide Schizophrenia Risk Variants on Cortical Neuroimaging Phenotypes.
  Voineskos Aristotle N, et al. Schizophrenia bulletin 2015 12

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Relevant Resources

• Cancer Genomics and Epidemiology Navigator (CGEN)
• Genetics and Genomics Competencies Center (G2C2)
• NIH Genetic Testing Registry
• NIH MedGen Database
• Online Mendelian Inheritance in Man (OMIM)
• PharmGKB