Alzheimer's disease ► Public Health Genomics Knowledge Base (v1.0)

Public Health Genomics Knowledge Base (v1.0)














Last Updated: Apr 28, 2016

• The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable.
  Mez Jesse, et al. Neurobiology of aging 2016 5 115-21
• EEG-directed connectivity from posterior brain regions is decreased in dementia with Lewy bodies: a comparison with Alzheimer's disease and controls.
  Dauwan Meenakshi, et al. Neurobiology of aging 2016 5 122-9
• Association of genetic risk factors with cognitive decline: the PATH through life project.
  Andrews Shea J, et al. Neurobiology of aging 2016 5 150-8
• Dementia and Rapid Mortality: Who is at Risk?
  Staekenborg Salka S, et al. Journal of Alzheimer's disease : JAD 2016 4
• CHRNA7 Gene and Response to Cholinesterase Inhibitors in an Italian Cohort of Alzheimer's Disease Patients.
  Clarelli Ferdinando, et al. Journal of Alzheimer's disease : JAD 2016 4
• Gene Prioritization for Imaging Genetics Studies Using Gene Ontology and a Stratified False Discovery Rate Approach.
  Patel Sejal, et al. Frontiers in neuroinformatics 2016 0 14
• Influence of APOE Genotype on Alzheimer's Disease CSF Biomarkers in a Spanish Population.
  Monge-Argilés J A, et al. BioMed research international 2016 0 1390620
• No association of the variant rs11887120 in DNMT3A with cognitive decline in individuals with mild cognitive impairment.
  Bey Katharina, et al. Epigenomics 2016 4
• Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease.
  Yokoyama Jennifer S, et al. JAMA neurology 2016 4
• The GBA, DYRK1A and MS4A6A polymorphisms influence the age at onset of Chinese Parkinson patients.
  Fan Kuan, et al. Neuroscience letters 2016 4 133-136
• Mutation analysis of the MS4A and TREM gene clusters in a case-control Alzheimer's disease data set.
  Ghani Mahdi, et al. Neurobiology of aging 2016 3
• Polymorphisms of small ubiquitin-related modifier genes are associated with risk of Alzheimer's disease in Korean: A case-control study.
  Mun Myung-Jin, et al. Journal of the neurological sciences 2016 5 122-7
• Plasma Ceramides and Neuropsychiatric Symptoms of Alzheimer's Disease.
  Xing Yi, et al. Journal of Alzheimer's disease : JAD 2016 4
• The Effect of Propofol Versus Isoflurane Anesthesia on Human Cerebrospinal Fluid Markers of Alzheimer's Disease: Results of a Randomized Trial.
  Berger Miles, et al. Journal of Alzheimer's disease : JAD 2016 4
• Common variant in PTK2B is associated with late-onset Alzheimer's disease: A replication study and meta-analyses.
  Li Ya-Qing, et al. Neuroscience letters 2016 4 83-87
• Relevance of defensin ?-2 and ? defensins (HNP1-3) in Alzheimer's disease.
  Szekeres Martha, et al. Psychiatry research 2016 3 342-345
• ApoE and SNAP-25 Polymorphisms Predict the Outcome of Multidimensional Stimulation Therapy Rehabilitation in Alzheimer's Disease.
  Guerini Franca Rosa, et al. Neurorehabilitation and neural repair 2016 4
• Development of a Melting Curve-Based Allele-Specific PCR of Apolipoprotein E (APOE) Genotyping Method for Genomic DNA, Guthrie Blood Spot, and Whole Blood.
  Chen Chia-Hsiang, et al. PloS one 2016 0 (4) e0153593
• A rare coding variant in TREM2 increases risk for Alzheimer's disease in Han Chinese.
  Jiang Teng, et al. Neurobiology of aging 2016 3
• [Levels of proinflammatory cytokines and vascular endothelial growth factor in patients with Alzheimer's disease and mild cognitive impairment].
  Malashenkova I K, et al. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova / Ministerstvo zdravookhraneniia i meditsinskoi promyshlennosti Rossiiskoi Federatsii, Vserossiiskoe obshchestvo nevrologov [i] Vserossiiskoe obshchestvo psikhiatrov 0 0 (3) 39-43
• Association study between the DNMT3A -448A>G polymorphism and risk of Alzheimer's disease in Caucasians of Italian origin.
  Tannorella Pierpaola, et al. American journal of neurodegenerative disease 2016 0 (1) 85-93
• The presenilin 1 p.Gly206Ala mutation is a frequent cause of early-onset Alzheimer's disease in Hispanics in Florida.
  Ravenscroft Thomas A, et al. American journal of neurodegenerative disease 2016 0 (1) 94-101
• Searching for Primary Predictors of Conversion from Mild Cognitive Impairment to Alzheimer's Disease: A Multivariate Follow-Up Study.
  López María Eugenia, et al. Journal of Alzheimer's disease : JAD 2016 3
• APOE, MAPT, and COMT and Parkinson's Disease Susceptibility and Cognitive Symptom Progression.
  Paul Kimberly C, et al. Journal of Parkinson's disease 2016 4
• Influence of APOE Genotype on Hippocampal Atrophy over Time - An N=1925 Surface-Based ADNI Study.
  Li Bolun, et al. PloS one 2016 0 (4) e0152901
• Apolipoprotein E Genotype and Sex Influence Glucose Tolerance in Older Adults: A Cross-Sectional Study.
  Hanson Angela J, et al. Dementia and geriatric cognitive disorders extra 0 0 (1) 78-89
• Genetic Association between Presenilin 2 Polymorphisms and Alzheimer's Disease and Dementia of Lewy Body Type in a Japanese Population.
  Suzuki Ayako, et al. Dementia and geriatric cognitive disorders extra 0 0 (1) 90-7
• Alzheimer risk genes modulate the relationship between plasma apoE and cortical PiB binding.
  Lazaris Andreas, et al. Neurology. Genetics 2015 10 (3) e22
• Effects of HLA-DRB1/DQB1 Genetic Variants on Neuroimaging in Healthy, Mild Cognitive Impairment, and Alzheimer's Disease Cohorts.
  Wang Zi-Xuan, et al. Molecular neurobiology 2016 4
• Genetic Association of HLA Gene Variants with MRI Brain Structure in Alzheimer's Disease.
  Wang Zi-Xuan, et al. Molecular neurobiology 2016 4

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Relevant Resources

• Cancer Genomics and Epidemiology Navigator (CGEN)
• Genetics and Genomics Competencies Center (G2C2)
• NIH Genetic Testing Registry
• NIH MedGen Database
• Online Mendelian Inheritance in Man (OMIM)
• PharmGKB