Aging UPDATE| June 30 - July 7, 2016 | Public Health Genomics Knowledge Base (v1.0)

Public Health Genomics Knowledge Base (v1.0)



June 30 - July 7, 2016 




Last Updated: Jun 30, 2016

• Human ApoE ?2 Promotes Regulatory Mechanisms of Bioenergetic and Synaptic Function in Female Brain: A Focus on V-type H+-ATPase.
  Woody Sarah K, et al. Journal of Alzheimer's disease : JAD 2016 6
• Lower Late-Life Body-Mass Index is Associated with Higher Cortical Amyloid Burden in Clinically Normal Elderly.
  Hsu David C, et al. Journal of Alzheimer's disease : JAD 2016 6
• Effect of a Leucine-rich Repeat Kinase 2 Variant on Motor and Non-motor Symptoms in Chinese Parkinson's Disease Patients.
  Sun Qian, et al. Aging and disease 2016 5 (3) 230-6
• Lack of functional KL-VS polymorphism of the KLOTHO gene in the Korean population.
  Kim Hee-Kwon, et al. Genetics and molecular biology 2016 6 0
• Proteolytic Cleavage of Apolipoprotein E in the Down Syndrome Brain.
  Day Ryan J, et al. Aging and disease 2016 5 (3) 267-77
• GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium.
  Matteini Amy M, et al. Aging cell 2016 6
• APOE and aging-related cognitive change in a longitudinal cohort of men.
  Rantalainen Ville, et al. Neurobiology of aging 2016 8 151-8
• Impaired fasting glucose is associated with increased regional cerebral amyloid.
  Morris Jill K, et al. Neurobiology of aging 2016 8 138-42
• Telomere-associated aging disorders.
  Opresko Patricia L et al. Ageing research reviews 2016 May
• The Healthy Aging Data Portal 
• Analyses MAPT, GRN, and C9orf72 mutations in Chinese patients with frontotemporal dementia.
  Tang Min, et al. Neurobiology of aging 2016 5
• The Healthy Aging Data Portal 
• Focus on Aging
  Cell Metabolism
• Genes for a ‘Wellderly’ Life
  JSK Kauwe et al, Cell Metabolism, June 2016
• Genetic Variants of the FADS Gene Cluster Are Associated with Erythrocyte Membrane LC PUFA Levels in Patients with Mild Cognitive Impairment.
  Schuchardt J P, et al. The journal of nutrition, health & aging 2016 0 (6) 611-20

• CDC Information (6)
• CDC-Authored Pub (2)

• Human (22)
• Pathogen (1)

• Human (3024)
• Pathogen (0)

• Human (14)
• Pathogen (0)

• Guidelines (1)
• Tier Table (0)
• Synthesis (2)

• Implementation (1)

Relevant Resources

• Cancer Genomics and Epidemiology Navigator (CGEN)
• Genetics and Genomics Competencies Center (G2C2)
• NIH Genetic Testing Registry
• NIH MedGen Database
• Online Mendelian Inheritance in Man (OMIM)
• PharmGKB