Evaluation of Birth Weight and Neurodevelopmental Conditions Among Monozygotic and Dizygotic Twins. Johan Isaksson et al. JAMA Netw Open 2023 6 (6) e2321165

After adjustment for genetic factors, is birth weight associated with neurodevelopmental conditions? In this case-control study of 393 twins in Sweden, the twin with a lower birth weight in monozygotic twin pairs, but not dizygotic pairs, had more autism and attention-deficit/hyperactivity disorder (ADHD) symptoms, lower IQ ratings, and higher odds of having a diagnosis of autism and ADHD compared with their co-twin. These findings suggest that birth weight contributes to neurodevelopmental conditions when adjusting for genetic factors. https://phgkb.cdc.gov/PHGKB/phgHome.action?query=Developmental%20disabilities&action=search&Mysubmit=Search