Cyclosporine a directly affects human and mouse b cell migration in vitro by disrupting a hIF-1 α dependent, o 2 sensing, molecular switch | BMC Immunology | Full Text

Cyclosporine a directly affects human and mouse b cell migration in vitro by disrupting a hIF-1 α dependent, o 2 sensing, molecular switch | BMC Immunology | Full Text

Cyclosporine a directly affects human and mouse b cell migration in vitro by disrupting a hIF-1 αdependent, o2 sensing, molecular switch

Hypoxia is a potent molecular signal for cellular metabolism, mitochondrial function, and migration. Conditions of low oxygen tension trigger regulatory cascades mediated via the highly conserved HIF-1 α post-tra...

Authors:Shannon P Hilchey, Mukta G Palshikar, Jason A Emo, Dongmei Li, Jessica Garigen, Jiong Wang, Eric S Mendelson, Valentina Cipolla, Juilee Thakar and Martin S Zand

Citation:BMC Immunology 2020 21:13

Content type:Research Article

Published on: 18 March 2020

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