Latest Arthritis & Rheumatology News and Research
Researchers caution use of chloroquine therapy for patients at higher risk of heart rhythm abnormalities
A patient who met many of the published safety guidelines for chloroquine therapy against COVID-19 was observed to have a very abnormal ECG pattern after treatment began, leading to multiple episodes of torsade de pointes (TdP), a life-threatening arrhythmia in which the lower chambers of the heart beat out of sync with the upper chambers.
DFG establishes interdisciplinary commission to strengthen pandemic research
Against the background of the current coronavirus pandemic, the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is to establish an interdisciplinary commission for pandemic research.
Repurposing immunosuppressants to manage COVID-19
It might seem paradoxical to suggest immunosuppression could play a role in managing COVID-19. The seemingly logical therapeutic option for this disease would be an antiviral.
Early intensive treatment of rheumatoid arthritis offers an opportunity to manage fatigue
Disease-related, profound fatigue impairs the quality of life of many people with rheumatic and musculoskeletal diseases.
Anti-TNF drug preserves beta-cell function in newly diagnosed pediatric patients with Type 1 diabetes
In research led by a University at Buffalo pediatric endocrinologist, a drug called golimumab showed that it preserved beta-cell function in children and young adults with newly diagnosed Type 1 diabetes, according to findings from a Phase 2 study.
Researchers create superior bone grafts using primitive stem cells
Although most broken bones can be mended with a firm cast and a generous measure of tender loving care, more complicated fractures require treatments like bone grafting.
Research team generates comprehensive developmental map of human T-cells
Chintan Parekh, MD, of The Saban Research Institute of Children's Hospital Los Angeles, has led a team of investigators that generated a comprehensive roadmap for how T-cells develop in the human thymus.
Irregular circadian rhythm in older adults associated with increased risk of Parkinson's disease
Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson's disease, according to a new study by scientists at the UC San Francisco Weill Institute for Neurosciences who analyzed 11 years of data for nearly 3,000 independently living older men.
Corrona Psoriasis Registry to present studies at AAD Virtual Meeting Experience
The Corrona® Psoriasis Registry, a joint collaboration between the National Psoriasis Foundation, NPF, and Corrona, LLC, the leading sponsor of registries in immune-mediated diseases, announces that studies from the registry will be presented at the American Academy of Dermatology Virtual Meeting Experience taking place June 12-14, 2020.
Study initiates hydroxychloroquine clinical trial to prevent COVID-19 in healthy people
Rush University Medical Center has opened enrollment for a new clinical trial investigating whether the drug hydroxychloroquine is better than a placebo in preventing COVID-19 infection in healthy people working in health care settings.
Telemedicine helps patients with chronic pain receive support during lockdown
The covid-19 pandemic has exacerbated conditions for people living with chronic pain around the world and its long-term consequences are likely to be substantial, according to a new paper from researchers at the University of Bath's Centre for Pain Research.
Turning autoimmunity drugs into anti-cancer treatments
Professor Mark Cragg speaks to News-Medical about his research which involves turning autoimmunity drugs into anti-cancer treatments.
Hydroxychloroquine suppresses 'trained immunity'
A new study published on the preprint server medRxiv in June 2020 shows that the drug hydroxychloroquine (HCQ) suppresses a form of immunity called ‘trained immunity,’ with repercussions for its potential use to treat COVID-19.
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Immune modulation can cure severe and often fatal fungal infection in children
In the June 11 issue of the New England Journal of Medicine, a team of UCLA physicians and scientists describes the first case of immune modulation being used to cure a severe and often fatal fungal infection.
Mozart listening associated with reduced seizure frequency in patients with epilepsy
A new clinical research study by Dr. Marjan Rafiee and Dr. Taufik Valiante of the Krembil Brain Institute at Toronto Western Hospital, part of University Health Network, has found that a Mozart composition may reduce seizure frequency in patients with epilepsy.
Tocilizumab in Critical COVID-19 Patients
A new study by scientists at Metro Infectious Disease Consultants and published on the preprint server medRxiv* in June 2020 reports that the cytokine blocker tocilizumab is a useful adjunct to supportive medical care in severe COVID-19, with increased survival and a lower requirement for mechanical ventilation.
Immuno-oncology may accelerate the development of treatments for COVID-19
Researchers at Roswell Park Comprehensive Cancer Center have been actively engaged in the effort to develop treatments or other control strategies that can help communities worldwide to address the impacts of the COVID-19 pandemic.
Deployment of health care professionals can improve inflammatory-rheumatic disorders
Inflammatory-rheumatic disorders are a widespread ailment, affecting at least 1.5 million people in Germany alone.
A drug to treat harsh complications of coronavirus infection is registered in Russia
Levilimab received state approval through a fast-track mechanism, according to Decree No. 441 of the Government of the Russian Federation of April 4, 2020, since its mechanism of action is associated with the control of the cytokine storm, which is one of the manifestations of coronavirus infection.
Study unravels role of a protein in osteoclast generation
Bone-dissolving cells called osteoclasts are derived from a type of immune cells called macrophages. They are necessary for the maintenance and renewal of bones.
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