SARS-CoV-2 sequence typing, evolution and signatures of selection using CoVa, a Python-based command-line utility
F Ali et al, BIORXIV, June 12, 2020
F Ali et al, BIORXIV, June 12, 2020
Broad-Range Virus Detection and Discovery Using Microfluidic PCR Coupled with High-throughput Sequencing
Y Tao et al BIORXIV, June 12, 2020
Y Tao et al BIORXIV, June 12, 2020
The impact of super-spreaders in COVID-19: mapping genome variation worldwide
A Gomez-Carballa et al, BIORXIV, June 12, 2020
A Gomez-Carballa et al, BIORXIV, June 12, 2020
Effects of Renin-Angiotensin Inhibition on ACE2 and TMPRSS2 Expression
C Wu et al, BIORXIV, June 12, 2020
C Wu et al, BIORXIV, June 12, 2020
Machine Learning Maps Research Needs in COVID-19 Literature
AL Doanvo et al, BIORXIV, June 12, 2020
AL Doanvo et al, BIORXIV, June 12, 2020
Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early prognostic marker for severe COVID-19
G Carissimo et al, BIORXIV, June 12, 2020
G Carissimo et al, BIORXIV, June 12, 2020
The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity
L Zhang et al, BIORXIV, June 12, 2020
L Zhang et al, BIORXIV, June 12, 2020
Profiling the positive detection rate of SARS-CoV-2 using polymerase chain reaction in different types of clinical specimens: a systematic review and meta-analysis
GM Bwire et al, MEDRXIV, June 12, 2020
GM Bwire et al, MEDRXIV, June 12, 2020
Evolution and epidemic spread of SARS-CoV-2 in Brazil
D da Silva Candido et al, MEDRXIV, June 12, 2020
D da Silva Candido et al, MEDRXIV, June 12, 2020
Detection of SARS-CoV-2 in wastewater in Japan by multiple molecular assays-implication for wastewater-based epidemiology (WBE)
A Hata et al, MEDRXIV, June 12, 2020
A Hata et al, MEDRXIV, June 12, 2020
An imperfect tool: COVID-19 'test & trace' success relies on minimising the impact of false negatives and continuation of physical distancing.
EL Davis et al, MEDRXIV, June 13, 2020
EL Davis et al, MEDRXIV, June 13, 2020
Initial Whole Genome Sequencing and Analysis of the Host Genetic Contribution to COVID-19 Severity and Susceptibility
F Wang et al, MEDRXIV, June 13, 2020
F Wang et al, MEDRXIV, June 13, 2020
This is the first host genetic study in China by deeply sequencing the 332 COVID-19 patients categorized by varying levels of severity. Gene loci associated with severity is located in TMEM189-UBE2V1 involved in the IL-1 signaling pathway. The p.Val197Met missense variant that affects the stability of the TMPRSS2 protein displays a decreasing allele frequency.
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