domingo, 21 de junio de 2020

Do Your Genes Place You At High Risk For COVID-19? E Matloff, Forbes, June 17, 2020

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Coronavirus

Could our genes factor into who gets COVID-19, gets very sick or dies from the condition, and who does not? Preliminary data from several early studies now point to yes.
We estimate that susceptibility to infection in individuals under 20 years of age is approximately half that of adults aged over 20 years, and that clinical symptoms manifest in 21% of infections in 10- to 19-year-olds, rising to 69% of infections in people aged over 70 years. Interventions aimed at children might have a relatively small impact on reducing transmission.
Disease and healthcare burden of COVID-19 in the United States
IF Miller et al, Nature Medicine, June 16, 2020
Dr. Priya Duggal will discuss what we know and don’t know about the role of host genomics in COVID-19, as well as ongoing initiatives and studies that are seeking to assess the role of host genomics in COVID-19. She will also discuss the potential public health impact of host genomics in COVID-19 and the importance of sound epidemiological study designs.
In a large trial, a cheap and widely available steroid cut deaths by one-third among patients critically ill with COVID-19.
One of the most crucial questions about an emerging infectious disease such as the new coronavirus is how deadly it is. After months of collecting data, scientists are getting closer to an answer.

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