Coronavirus Disease Portal|Home|PHGKB

Coronavirus Disease Portal|Home|PHGKB

 Spotlight on COVID-19

Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals
Y Liu et al, Nature, April 27, 2020

This study investigated the aerodynamic nature of SARS-CoV-2 by measuring viral RNA in aerosols in different areas of two Wuhan hospitals during the COVID-19 outbreak in February and March 2020. The concentration of SARS-CoV-2 RNA in aerosols detected in isolation wards and ventilated patient rooms was very low, but it was elevated in the patients’ toilet areas.

The computer algorithm that was among the first to detect the coronavirus outbreak
CBS 60 Minutes, April 26, 2020

On New Year's Eve, a small company in Canada was among the first to raise the alarm about an infectious disease outbreak. Its computer algorithm calculated where the virus might spread next. The technology could change the way we fight another contagion.

Using ILI surveillance to estimate state-specific case detection rates and forecast SARS-CoV-2 spread in the United States
JD Silverman et al, MEDRXIV, April 26, 2020

Publicly available data can be repurposed to estimate the detection rate of symptomatic SARS-CoV-2 infections. We find a surge of non-influenza ILI above the seasonal average and show that this surge is correlated with COVID case counts across states. We estimate the syndromic case detection rate of SARS-CoV-2 in the US to be less than 13%.

Plasma Metabolomic and Lipidomic Alterations Associated with COVID-19
D Wu et al, MEDRXIV, April 26, 2020

In this study, we performed targeted metabolomic and lipidomic analyses of plasma from a cohort of COVID-19 patients who had experienced different symptoms. We found the metabolite and lipid alterations exhibit apparent correlation with the course of disease in these COVID-19 patients.