KLF4 K409Q –mutated meningiomas show enhanced hypoxia signaling and respond to mTORC1 inhibitor treatment | Acta Neuropathologica Communications | Full Text

KLF4 K409Q –mutated meningiomas show enhanced hypoxia signaling and respond to mTORC1 inhibitor treatment | Acta Neuropathologica Communications | Full Text

KLF4K409Q–mutated meningiomas show enhanced hypoxia signaling and respond to mTORC1 inhibitor treatment

Meningioma represents the most common primary brain tumor in adults. Recently several non-NF2 mutations in meningioma have been identified and correlated with certain pathological subtypes, locations and clinical...

Authors:Niklas von Spreckelsen, Natalie Waldt, Rebecca Poetschke, Christoph Kesseler, Hildegard Dohmen, Hui-Ke Jiao, Attila Nemeth, Stefan Schob, Cordula Scherlach, Ibrahim Erol Sandalcioglu, Martina Deckert, Frank Angenstein, Boris Krischek, Pantelis Stavrinou, Marco Timmer, Marc Remke…

Citation:Acta Neuropathologica Communications 2020 8:41

Content type:Research

Published on: 3 April 2020

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