Liquid Biopsy and its Role in Cancer Prevention

PubMed Clinical Queries

Caption: DNA (blue) loops around nucleosomes (gray) and is bound by transcription factors (red), proteins that switch genes on and off and act in a tissue-specific manner. When cells die, enzymes (scissors) chop up areas between the nucleosomes and transcription factors, releasing DNA fragments in unique patterns. By gathering the released DNA fragments in blood, researchers can tell which types of cells produced them.
Credit: Shendure Lab/University of Washington

From PubMed Clinical Queries

PubMed Clinical Queries is an utility offered by PubMed to search scientific literature in specific clinical research areas

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• Search PubMed Clinical Queries for "Liquid biopsy" 

Results: 5 of 723

• Serum metabolic profiling identified a distinct metabolic signature in patients with idiopathic pulmonary fibrosis - a potential biomarker role for LysoPC.
  Rindlisbacher B, Schmid C, Geiser T, Bovet C, Funke-Chambour M.Respir Res. 2018 Jan 10; 19(1):7. Epub 2018 Jan 10.
• A multicenter prospective study on the diagnostic performance of a new liquid rapid urease test for the diagnosis of <i>Helicobacter pylori</i> infection.
  Dolak W, Bilgilier C, Stadlmann A, Leiner J, Püspök A, Plieschnegger W, Siebert F, Wewalka F, Schöfl R, Huber-Schönauer U, et al.Gut Pathog. 2017; 9:78. Epub 2017 Dec 22.
• Repeat biopsy in epidermal growth factor receptor mutation-positive nonsmall cell lung cancer: Feasibility, limitations, and clinical utility in Indian patients.
  Zanwar S, Noronha V, Joshi A, Patil VM, Chougule A, Kumar R, More S, Goud S, Janu A, Mahajan A, et al.Indian J Cancer. 2017 Jan-Mar; 54(1):280-284.
• TARIBO trial: targeted therapy with or without nephrectomy in metastatic renal cell carcinoma: liquid biopsy for biomarkers discovery.
  Verzoni E, Ratta R, Grassi P, Salvioni R, Stagni S, Montone R, Fucà G, Cappelletti V, Reduzzi C, De Giorgi U, et al.Tumori. 2017 Nov 29; :0. Epub 2017 Nov 29.
• Osimertinib - effective treatment of NSCLC with activating <i>EGFR</i> mutations after progression on EGFR tyrosine kinase inhibitors.
  Skrzypski M, Szymanowska-Narloch A, Dziadziuszko R.Contemp Oncol (Pozn). 2017; 21(3):254-258. Epub 2017 Sep 29.

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Medical Genetics

Topic:AllDiagnosisDifferential DiagnosisClinical DescriptionManagementGenetic CounselingMolecular GeneticsGenetic Testing

Results: 5 of 829

• Molecular profiling of lung cancer specimens and liquid biopsies using MALDI-TOF mass spectrometry.
  Bonaparte E, Pesenti C, Fontana L, Falcone R, Paganini L, Marzorati A, Ferrero S, Nosotti M, Mendogni P, Bareggi C, et al.Diagn Pathol. 2018 Jan 12; 13(1):4. Epub 2018 Jan 12.
• LGALS4, CEACAM6, TSPAN8, and COL1A2: Blood Markers for Colorectal Cancer-Validation in a Cohort of Subjects With Positive Fecal Immunochemical Test Result.
  Rodia MT, Solmi R, Pasini F, Nardi E, Mattei G, Ugolini G, Ricciardiello L, Strippoli P, Miglio R, Lauriola M.Clin Colorectal Cancer. 2017 Dec 12; . Epub 2017 Dec 12.
• Development of a predictive miRNA signature for breast cancer risk among high-risk women.
  Farina NH, Ramsey JE, Cuke ME, Ahern TP, Shirley DJ, Stein JL, Stein GS, Lian JB, Wood ME.Oncotarget. 2017 Dec 22; 8(68):112170-112183. Epub 2017 Nov 28.
• Evaluation of nipple aspirate fluid as a diagnostic tool for early detection of breast cancer.
  Shaheed SU, Tait C, Kyriacou K, Linforth R, Salhab M, Sutton C.Clin Proteomics. 2018; 15:3. Epub 2018 Jan 11.
• A myopic perspective on the future of protein diagnostics.
  Landegren U, Al-Amin RA, Björkesten J.N Biotechnol. 2018 Jan 5; . Epub 2018 Jan 5.

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This column displays citations pertaining to topics in medical genetics. See more filter information.

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