Cell-free DNA analysis reveals POLR1D -mediated resistance to bevacizumab in colorectal cancer | Genome Medicine | Full Text

Cell-free DNA analysis reveals POLR1D -mediated resistance to bevacizumab in colorectal cancer | Genome Medicine | Full Text

Cell-free DNA analysis reveals POLR1D-mediated resistance to bevacizumab in colorectal cancer

Bevacizumab, a monoclonal antibody against soluble VEGFA, is an approved and commonly administered anti-angiogenic drug in patients with metastasized colorectal cancer (mCRC). The survival benefit of anti-VEGF...

Authors:Qing Zhou, Samantha O. Perakis, Peter Ulz, Sumitra Mohan, Jakob M. Riedl, Emina Talakic, Sigurd Lax, Martin Tötsch, Gerald Hoefler, Thomas Bauernhofer, Martin Pichler, Armin Gerger, Jochen B. Geigl, Ellen Heitzer and Michael R. Speicher

Citation:Genome Medicine 2020 12:20

Content type:Research

Published on: 22 February 2020

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