DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations | Acta Neuropathologica Communications | Full Text

DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations | Acta Neuropathologica Communications | Full Text

DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations

DNA damage is implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS). However, relationships between DNA damage accumulation, DNA damage response (DDR), and upper and lower motor neuron vulnerab...

Authors:Byung Woo Kim, Ye Eun Jeong, Margaret Wong and Lee J. Martin

Citation:Acta Neuropathologica Communications 2020 8:7

Content type:Research

Published on: 31 January 2020

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