H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade | Clinical Epigenetics | Full Text

H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade | Clinical Epigenetics | Full Text

H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade

Upregulation of the histone methyltransferase enzyme EZH2 and its histone modification H3K27me3 has been linked to melanoma progression, metastasis, and resistance to immune checkpoint blockade (ICB). In clini...

Authors:Friederike Hoffmann, Dennis Niebel, Pia Aymans, Sandra Ferring-Schmitt, Dimo Dietrich and Jennifer Landsberg

Citation:Clinical Epigenetics 2020 12:24

Content type:Research

Published on: 10 February 2020

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