Coronavirus [NEW TOPIC PAGE]

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 Coronavirus

The Challenge of Tracking COVID-19’s Stealthy Spread
NIH Director's Blog, April 23, 2020

NIAID strategic plan details COVID-19 research priorities
NIH, April 23, 2020 

This include four key priorities. The first involves improving fundamental knowledge of virus including studies to characterize the virus and better understand how it causes infection and disease. This includes natural history, transmission studies to determine why some individuals experience mild symptoms while others become critically ill.

Community and Socioeconomic Factors Associated with COVID-19 in the United States: Zip code level cross sectional analysis
A Guha et al, MEDRXIV, April 22, 2020

Researchers Study Why Men Seem To Be More Affected By COVID-19
NPR, April 23, 2020

Detection of SARS-CoV-2 RNA by direct RT-qPCR on nasopharyngeal specimens without extraction of viral RNA
MR Hasan et al, MEDRXIV, April 23, 2020

The Novel Coronavirus Disease (COVID-19): A PRISMA Systematic Review and Meta-analysis of Clinical and Paraclinical characteristics
H Hazani et al, MEDRXIV, April 23, 2020

Identification of super-transmitters of SARS-CoV-2
X Yang et al, MEDRXIV, April 23, 2020

Four genetic clusters defined as Super-transmitters (STs) were found to become dominant and were responsible for the major outbreaks in various countries.

Population genomics insights into the recent evolution of SARS-CoV-2
M Vasilarou et al, BIORXIV, April 23, 2020

In this study, we used population genetics analysis to infer the mutation rate and plausible recombination events that may have contributed to the evolution of the SARS-CoV-2 virus. Furthermore, we localized targets of recent and strong positive selection.

Is ethnicity linked to incidence or outcomes of covid-19?
BMJ Editorial, April 20, 2020

Ethnic minority groups have been disproportionately affected by covid-19 in the US, highlighting potential racial, economic, and other inequalities.