Frontotemporal disorders (FTD) are the most common cause of dementia in people younger than 60. This family of diseases has a strong genetic component with over one-third of cases being inherited.
Scientists have recently published a study analyzing data from the U.S., Europe, Canada and Australia to explore how genetics and family history relate to the age of onset and disease duration in FTD.
The study identified that certain gene mutations were associated with younger age of onset and death. Understanding the causes of variation in age of onset could provide important clues about what causes FTD. This data could also help inform interventions for people before symptoms appear.
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