High level MYCN amplification and distinct methylation signature define an aggressive subtype of spinal cord ependymoma | Acta Neuropathologica Communications | Full Text

High level MYCN amplification and distinct methylation signature define an aggressive subtype of spinal cord ependymoma | Acta Neuropathologica Communications | Full Text

High level MYCN amplification and distinct methylation signature define an aggressive subtype of spinal cord ependymoma

We report a novel group of clinically aggressive spinal cord ependymomas characterized by Grade III histology, MYCN amplification, an absence of NF2 alterations or other recurrent pathogenic mutations, and a uniq...

Authors:Mark Raffeld, Zied Abdullaev, Svetlana D. Pack, Liqiang Xi, Sushma Nagaraj, Nicole Briceno, Elizabeth Vera, Stefania Pittaluga, Osorio Lopes Abath Neto, Martha Quezado, Kenneth Aldape, Terri S. Armstrong and Mark R. Gilbert

Citation:Acta Neuropathologica Communications 2020 8:101

Content type:Research

 

Published on: 8 July 2020

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