Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation | Acta Neuropathologica Communications | Full Text

Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation | Acta Neuropathologica Communications | Full Text

Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation

During brain development, the nucleus of migrating neurons follows the centrosome and translocates into the leading process. Defects in these migratory events, which affect neuronal migration, cause lissenceph...

Authors:Meng-Han Tsai, Haw-Yuan Cheng, Fang-Shin Nian, Chen Liu, Nian-Hsin Chao, Kuo-Liang Chiang, Shu-Fang Chen and Jin-Wu Tsai

Citation:Acta Neuropathologica Communications 2020 8:106

Content type:Research

 

Published on: 14 July 2020

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