Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy | BMC Cancer | Full Text

Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy | BMC Cancer | Full Text

Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy

Based on its low toxicity, arginine starvation therapy has the potential to cure malignant tumors that cannot be treated surgically. The Arginine deiminase (ADI) gene has been identified to be an ideal cancer-...

Authors:Qingyuan Feng, Xuzhao Bian, Xuan Liu, Ying Wang, Huiting Zhou, Xiaojing Ma, Chunju Quan, Yi Yao and Zhongliang Zheng

Citation:BMC Cancer 2020 20:665

Content type:Research article

 

Published on: 16 July 2020

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