lunes, 6 de julio de 2020

Making sense of mutation: what D614G means for the COVID-19 pandemic remains unclear ND Grubaugh et al. Cell, July 2, 2020

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Coronavirus

A SARS-CoV-2 variant with Spike G614 has replaced D614 as the dominant pandemic form- The consistent increase of G614 at regional levels may indicate a fitness advantage- G614 is associated with lower RT PCR Ct’s, suggestive of higher viral loads in patients- The G614 variant grows to higher titers as pseudotyped virions.

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