ACE2 binding causes dissociation of trimeric SARS-CoV-2 spike, may be used to inhibit further infection

ACE2 binding causes dissociation of trimeric SARS-CoV-2 spike, may be used to inhibit further infection

ACE2 binding causes dissociation of trimeric SARS-CoV-2 spike, may be used to inhibit further infection

A recent study published on the preprint server bioRxiv in October 2020 shows that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binding to the human host receptor could cause the typical trimeric spike protein to come apart, forming a stable monomer instead with the receptor.