Coronavirus [NEW TOPIC PAGE]

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 Coronavirus

COVID-19 Trends Among School-Aged Children — United States, March 1–September 19, 2020
RT Leeb et al, CDC MMWR, September 28, 2020

Since March, 277,285 COVID-19 cases in children have been reported. COVID-19 incidence among adolescents aged 12–17 years was approximately twice that in children aged 5–11 years. Underlying conditions were more common among school-aged children with severe outcomes related to COVID-19. Data varied over time and by region of the United States.

Genetic variants mimicking therapeutic inhibition of IL-6 receptor signaling and risk of COVID-19
J Bovijn et al, Lancet Rheumatology, September 25, 2020

Our findings show that IL6R variants mimicking therapeutic inhibition of IL-6 receptor are associated with a lower risk of hospitalization for COVID-19, a phenotype that is associated with disease severity (eg, requiring supplemental oxygen is a typical reason for hospitalization).

Clinical Course And Risk Factors For In-hospital Death In Critical COVID-19 In Wuhan, China
F Li et al, MEDRXIV, September 28, 2020

A novel haemocytometric COVID-19 prognostic score developed and validated in an observational multicentre European hospital-based study
J Linssen et al, EDRXIV, September 28, 2020

A Systematic Review and Meta-analysis of Pregnancy and COVID-19: Signs and Symptoms, Laboratory Tests and Perinatal Outcomes
H Hassanipour et al, MEDRXIV, September 28, 2020

Different innate and adaptive immune response to SARS-CoV-2 infection of asymptomatic, mild and severe cases
R Carsetti, et al, MEDRXIV, September 28, 2020

Diagnosis value of SARS-CoV-2 antigen/antibody combined testing using rapid diagnostic tests at hospital admission
N Veyrenche et al, MEDRXIV, September 28, 2020

SalivaDirect: A simplified and flexible platform to enhance SARS-CoV-2 testing capacity
CBF Vogels et al, MEDRXIV, September 28, 2020