La acumulación de mutaciones en las mitocondrias que ocurre con la edad puede afectar negativamente a la función del corazón.

Cardiomyocyte-intrinsic somatic mtDNA mutations induce an OXPHOS-dependent immune response and promote progressive heart failure Kristina Bubb https://orcid.org/0000-0002-8457-0566, Giovanni Rigoni, Polyxeni Papadea https://orcid.org/0000-0002-5131-8196, Gianluigi Pironti https://orcid.org/0000-0001-9401-3029, Jelena Misic https://orcid.org/0000-0002-1562-0582, Shan Jiang https://orcid.org/0000-0003-2020-6447, David Alsina, Diana Rubalcava-Gracia https://orcid.org/0000-0002-4615-7375, Daniel C. Andersson https://orcid.org/0000-0003-4548-702X, [...] , and Nils-Göran Larsson https://www.science.org/doi/10.1126/sciadv.aec8606?utm_medium=email&_hsenc=p2ANqtz--nfdwC02MTaZIIuJzWrPmnL_X5sYIGl6BY846Ro0z08RRQjicDYd7ycQQ4w_7tELyrPO1rIs9Z7I9fgvtG0lpi1rqjhQ&_hsmi=145426708&utm_content=145428467&utm_source=hs_email