miércoles, 5 de diciembre de 2018

Host Cell Protein Analysis is Transitioning to a New Phase

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Host Cell Protein analysis is transitioning to a new phase

Host Cell Proteins (HCPs) are contaminants considered as Critical Quality Attributes in biotherapeutic drug preparations, and so must be monitored due to stability, efficacy and immunogenicity concerns.

Immunospecific assays such as ELISA are currently the gold standard for QC applications, but there are long lead times for new assays based on process changes.


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What to Expect

In this presentation, you will learn how PASEF (parallel accumulation and serial fragmentation), as implemented on the Bruker timsTOF PRO QTOF, can be applied to HCP analysis to achieve the goal of rapid and sensitive detection with quality data.

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