herenciageneticayenfermedad: Drug Discovery and Production | Medical News | Medical Articles

viernes, 6 de marzo de 2020

Drug Discovery and Production | Medical News | Medical Articles | Drug Discovery and Production |

	Drug Discovery and Production
	The latest drug discovery news from News Medical

Web-based Barcode Scanner Technology

In modern laboratories - samples are typically stored in large -80°C freezers, liquid nitrogen tanks or fully automated stores that are often inconveniently situated in an outbuilding or a basement. Datapaq 5 from Ziath is the first of a new generation of digital sample management tools that allows sample management technicians to quickly and accurately log sample identity at the point of storage or retrieval. Datapaq 5 offers a convenient way to use a 2D barcoded tube or rack scanner anywhere across a laboratory or an organisation’s site where a suitable laptop or computer is available. Running from any computer on a local network or over the internet if your IT rules allow, Datapaq 5 uses a web-based graphical user interface to provide visual confirmation of tube identity and individual tube image inspection. The new web-based software includes a host of features designed to streamline the collection of tube information for subsequent processing in inventory management software.

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Drug Discovery Workflow for PROTACs with a Focus on Eliminating Bottlenecks in Evaporation

PROTACs novel mode of action allows them to hijack a cells natural function and initiate degradation of the target protein for a particular disease. However, production of PROTACs requires numerous evaporation steps, causing bottlenecks in their production and slowing the drug development process.

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Recent Progress of In Vitro Toxicity Assays in Drug Discovery

Investigating the potential toxicity of any new drug is vital for its progress into the marketplace; however, the precise moment at which toxicity studies are performed during the drug development process can ultimately dictate its success or failure.

	Molecular Imaging in Drug Development While healthcare has made significant advancements over the last century, and medical professionals are more equipped than ever with the tools to treat a whole range of illnesses, the landscape of healthcare continues to evolve, and with this ever-changing environment comes the continued need for new drug candidates

	CRISPR-edited immune cells can be safely given to cancer patients The emergence of CRISPR-Cas9 gene-editing technology has spurred hope in both doctors and patients since it shows promise in treating a multitude of diseases, including cancer. For the first time in the United States, a team of scientists has shown that CRISPR-edited immune cells can be safely used to cancer patients.

	The research and development costs of a new drug Many recent studies have focused on how much it costs to bring a new drug to market in the light of increasing drug prices. Estimates range from $314 million to $2.8 billion. Most of this was based on proprietary data and was, therefore, not verifiable independently, attracting much criticism.