Loss of BICD2 in muscle drives motor neuron loss in a developmental form of spinal muscular atrophy | Acta Neuropathologica Communications | Full Text

Loss of BICD2 in muscle drives motor neuron loss in a developmental form of spinal muscular atrophy | Acta Neuropathologica Communications | Full Text

Loss of BICD2 in muscle drives motor neuron loss in a developmental form of spinal muscular atrophy

Autosomal dominant missense mutations in BICD2 cause Spinal Muscular Atrophy Lower Extremity Predominant 2 (SMALED2), a developmental disease of motor neurons. BICD2 is a key component of the cytoplasmic dynein/d...

Authors:Alexander M. Rossor, James N. Sleigh, Michael Groves, Francesco Muntoni, Mary M. Reilly, Casper C. Hoogenraad and Giampietro Schiavo

Citation:Acta Neuropathologica Communications 2020 8:34

Content type:Research

Published on: 17 March 2020

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