Principal component analysis of adipocytokines and insulin associate with risk factors of cardiovascular diseases
Obesity plays an important role in the development of chronic diseases like cardiovascular diseases and diabetes. The possible underlying mechanism for this connection is that adipose tissue secretes an array ...BMC Research Notes 2020 13:212Assessing two methods for estimating excess mortality of chronic diseases from aggregated data
To assess the numerical properties of two recently published estimation techniques for excess mortality based on aggregated data about diabetes in Germany.BMC Research Notes 2020 13:216BMPR-1B, BMP-15 and GDF-9 genes structure and their relationship with litter size in six sheep breeds reared in Egypt
The aim of this work was to investigate three different mutations; Fec-B, FecXG, Fec-GH at three candidate genes; Bone morphogenetic protein receptor IB, Bone morphogenetic protein 15 and Growth Differentiation F...BMC Research Notes 2020 13:215Single-site, five-year experience with human eosinophil isolation by density gradient centrifugation and CD16 immunomagnetic negative separation
Little has been reported regarding the reliability of methods for the purification of human blood eosinophils. We retrospectively reviewed our experience with 350 consecutive eosinophil isolations.BMC Research Notes 2020 13:211The cholesterol 24-hydroxylase activates autophagy and decreases mutant huntingtin build-up in a neuroblastoma culture model of Huntington’s disease
Compromised brain cholesterol turnover and altered regulation of brain cholesterol metabolism have been allied with some neurodegenerative diseases, including Huntington’s disease (HD). Following our previous ...BMC Research Notes 2020 13:210HIV patients dying on anti-tuberculosis treatment: are undiagnosed infections still a problem in French Guiana?
Despite scaling-up testing and antiretroviral treatment in Latin America, advanced HIV remains a significant public health problem. The objective of the present study was look for historical risk factors for d...BMC Research Notes 2020 13:209Green coffee extract modifies body weight, serum lipids and TNF-α in high-fat diet-induced obese rats
Currently, there are many efforts to find functional nutrients for obesity management, and the green coffee extract is a potential candidate. This study aimed to examine the effect of low dose administration o...BMC Research Notes 2020 13:208Practice on pressure ulcer prevention among nurses in selected public hospitals, Tigray, Ethiopia
Pressure ulcers are localized cellular damages to the skin and underlying tissues caused by pressure, shearing and frictional force. The aim of this study is to assess practices towards pressure ulcer preventi...BMC Research Notes 2020 13:207A recombinant antibody toolbox for Dictyostelium discoideum
The amoeba Dictyostelium discoideum has been a valuable model organism to study numerous facets of eukaryotic cell biology, such as cell motility, cell adhesion, macropinocytosis and phagocytosis, host–pathogen i...BMC Research Notes 2020 13:206Disease prediction via Bayesian hyperparameter optimization and ensemble learning
Early disease screening and diagnosis are important for improving patient survival. Thus, identifying early predictive features of disease is necessary. This paper presents a comprehensive comparative analysis...BMC Research Notes 2020 13:205Single center experience on implementation of the postpartum intrauterine device (PPIUD) in Sri Lanka: a retrospective study
to study the institutionalization of PPIUD services at Teaching Hospital, Mahamodara, Galle (THMG) and to study the feasibility, challenges and barriers for implementation.BMC Research Notes 2020 13:204The whole blood phagocytosis assay: a clinically relevant test of neutrophil function and dysfunction in community-acquired pneumonia
To refine and validate a neutrophil function assay with clinical relevance for patients with community-acquired pneumonia (CAP).BMC Research Notes 2020 13:203Blood Cd levels and carotid intima-media thickness in young adults living in Padang, Indonesia
Cd exposure is a non-traditional risk factor of cardiovascular disease and mortality by promoting the development of atherosclerosis. The development of atherosclerosis can be monitored non-invasively by measu...BMC Research Notes 2020 13:202Optimal control strategy for the effects of hard water consumption on kidney-related diseases
We study the optimal control strategy for the effects of hard water consumption on kidney-related diseases. The mathematical model has been formulated and studied to gain insights on the optimal control strate...BMC Research Notes 2020 13:201Development of the Japanese version of the Other As Shamer Scale using item response theory
External shame reflects a person’s anxiety that he or she might be rejected by others. The Other as Shamer Scale (OAS) is a scale for assessing external shame. The Japanese version of the OAS was developed, an...BMC Research Notes 2020 13:200Full-term low birth weight infants have differentially hypermethylated DNA related to immune system and organ growth: a comparison with full-term normal birth weight infants
Low birth weight (LBW) is a major public health issue as it increases the risk of noncommunicable diseases throughout life. However, the genome-wide DNA methylation patterns of full-term LBW infants (FT-LBWs) ...BMC Research Notes 2020 13:199The fiscal value of human lives lost from coronavirus disease (COVID-19) in China
According to the WHO coronavirus disease (COVID-19) situation report 35, as of 24th February 2020, there was a total of 77,262 confirmed COVID-19 cases in China. That included 2595 deaths. The specific objecti...BMC Research Notes 2020 13:198The effect of simulation-based training in non-physician anesthetists in Tigray region, Ethiopia
In Ethiopia simulation-based anesthesia education is a new way of teaching method which started in Mekelle University as of January, 2019. Hence, the purpose of this study is to evaluate whether simulation-bas...BMC Research Notes 2020 13:197Short-term prognostic value of TAPSE, RVFAC and Tricuspid S’ wave peak systolic velocity after first acute myocardial infarction
Right ventricular dysfunction impacts the prognosis of various heart diseases. We set-out to examine which right ventricular functional parameters after STEMI and NSTEMI have prognostic value. Of 297 eligible ...BMC Research Notes 2020 13:196Automated gene data integration with Databio
Although sequencing and other high-throughput data production technologies are increasingly affordable, data analysis and interpretation remains a significant factor in the cost of -omics studies. Despite the ...BMC Research Notes 2020 13:195The usefulness of C-reactive protein as a biomarker in predicting neonatal sepsis in a sub-Saharan African region
The early diagnosis of neonatal sepsis remains a challenge for physicians. The initiation or/and discontinuation of the empirical antibiotic therapy at neonates with sepsis is a dilemma due to the lack of defi...BMC Research Notes 2020 13:194SMASH standardised perioperative management of patients operated with acute abdominal surgery in a high-risk setting
Emergency laparotomy and other high-risk acute abdominal surgery procedures have a high mortality rate. The perioperative management of these patients is complex and poses several challenges. The objective of ...BMC Research Notes 2020 13:193Whole genome bisulfite sequencing of Medicago truncatula A17 wild type and lss mutants
Earlier work in our lab identified a spontaneous mutant (likesunnsupernodulator-lss) in Medicago truncatula, resulting in increased nodulation. Molecular genetic evidence indicated the phenotype was due to an unk...BMC Research Notes 2020 13:192Quantitative assessment of German Holstein dairy cattle colostrum and impact of thermal treatment on quality of colostrum viscosity and immunoglobulins
This study aimed to determine the color, fat, viscosity, IgG concentration, %Brix and refractive index of fresh postpartum colostrum of German Holstein dairy cattle and assess the impact of different thermal t...BMC Research Notes 2020 13:191Male involvement in prevention of mother to child transmission of human immuno virus and associated factors among partners’ of reproductive age women at Debre Tabor town, Northwest Ethiopia: a community based cross sectional study
The aim of this study was to determine the prevalence of male involvement in prevention of mother to child transmission (PMTCT) of human immune virus (HIV) and associated factors among partners’ of reproductiv...BMC Research Notes 2020 13:190Association between dietary energy density with mental health and sleep quality in women with overweight/obesity
Mental health, sleep quality, and dietary intake are interlinked. Impairment of mental health and low sleep quality may contribute to obesity through the consumption of diets high in energy density. Neverthele...BMC Research Notes 2020 13:189A naturally-occurring 22-bp coding deletion in Ugt86Dd reduces nicotine resistance in Drosophila melanogaster
Segregating genetic variants contribute to the response to toxic, xenobiotic compounds, and identifying these causative sites can help describe the mechanisms underlying metabolism of toxic compounds. In previ...BMC Research Notes 2020 13:188Rotavirus and Cryptosporidium pathogens as etiological proxies of gastroenteritis in some pastoral communities of the Amathole District Municipality, Eastern Cape, South Africa
Cryptosporidium and Rotavirus agents have been associated with severe diarrheal illnesses and remain as one of the worst human health burdens in most developing regions. In the present study, we evaluated the ...BMC Research Notes 2020 13:187Study determinants of increased Z-Score of Body Mass Index in preschool-age children
To determine the association between socioeconomic level, gender, stunting and other characteristics with the presence of overweight/obesity in the preschool children.BMC Research Notes 2020 13:186The study of factors associated with pregnancy outcomes in patients with systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disease that can lead to unfavorable pregnancy complications in women. This study aimed to evaluate the factors associated with pregnancy outcomes in patient...BMC Research Notes 2020 13:185Critical methodological considerations in recruiting and engaging non-native English speaking workers with a head injury: a Canadian perspective
Non-native English speaking workers with a mild work-related traumatic brain and/or head injury are a vulnerable and underrepresented population in research studies. The researchers present their experiences w...BMC Research Notes 2020 13:184Effects of pharmacist intervention on polypharmacy in patients with type 2 diabetes in Japan
Investigation of polypharmacy in patients with type 2 diabetes revealed that medications administered according to the patient’s symptoms and complaints strongly contributed to polypharmacy. We explored the ef...BMC Research Notes 2020 13:183The social health impact of Eritrean refugees on the host communities: the case of May-ayni refugee camp, Northern Ethiopia
Migration is a contemporary global issue and the exodus of refugees may potentially posit new social health challenges in the host communities. Ethiopia is a host to the second largest refugee population in Af...BMC Research Notes 2020 13:182Differences in expression of Peroxisome Proliferator-activated Receptor-γ in early-onset preeclampsia and late-onset preeclampsia
PPARγ is a ligand-binding transcription factor that has been reported to be implicated in lipid metabolism, immune function, and cellular growth and differentiation. It has been suspected to play a role in the...BMC Research Notes 2020 13:181The experience of polyethylene glycol (PEG) bowel preparation in adolescents undergoing colonoscopy
The aim of this study was to describe the experience of polyethylene glycol (PEG) bowel preparation in adolescents undergoing colonoscopy.BMC Research Notes 2020 13:180A comprehensive environmental scanning and strategic analysis of Iranian Public Hospitals: a prospective approach
This study was conducted to provide a strategic direction to public hospitals in Iran via environmental scanning in order to equip hospitals to plan and perform proactively and adapt with the everchanging envi...BMC Research Notes 2020 13:179AST/ALT ratio predicts the functional severity of chronic heart failure with reduced left ventricular ejection fraction
Despite previous research that focused on liver transaminases as predictors of cardiovascular disease, there has been limited research evaluating the predictive value of AST/ALT ratio in patients with heart fa...BMC Research Notes 2020 13:178Laparoscopic surgery for diverticular colovesical fistula: single-center experience of 11 cases
Laparoscopic surgery for diverticular colovesical fistula (CVF) is technically challenging, and the incidence of conversion to open surgery (COS) is high. This study aimed to review our experience with laparos...BMC Research Notes 2020 13:177Circulating tumour cell liquid biopsy in selecting therapy for recurrent cutaneous melanoma with locoregional pelvic metastases: a pilot study
Circulating tumour cells (CTCs) from liquid biopsies provide an exceptional opportunity to obtain real-time tumour information and are under current investigation in several cancers, including cutaneous melano...BMC Research Notes 2020 13:176Coagulation tests or standardized questionnaire, which is better as a predictor of bleeding? A prospective study among children before tonsillectomy and/or adenoidectomy
The value of pre-operative coagulation testing for adenotonsillar surgery is controversial. The purpose of this study was to evaluate the role of routine coagulation tests and a standardized questionnaire in c...BMC Research Notes 2020 13:175Challenges and practical recommendations for successfully recruiting inactive, statin-free older adults to clinical trials
To outline the challenges and provide practical recommendations for recruiting inactive, statin-free older adults to facilitate feasible study designs. Data was obtained from a double-blind randomised-controll...BMC Research Notes 2020 13:174Development, characterization, and cross-amplification of polymorphic microsatellite markers for North American Trachymyrmex and Mycetomoellerius ants
The objective of this study is to develop and identify polymorphic microsatellite markers for fungus-gardening (attine) ants in the genus Trachymyrmex sensu lato. These ants are important ecosystem engineers and ...BMC Research Notes 2020 13:173
viernes, 17 de abril de 2020
BMC Research Notes | Articles
BMC Research Notes | Articles
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