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jueves, 16 de abril de 2020

Drug Discovery and Production | Medical News | Medical Articles | Drug Discovery and Production |

	Drug Discovery and Production
	The latest drug discovery news from News Medical

How to Ensure Quantitative Accuracy in PET

Image quality is only one aspect of functional imaging with PET and SPECT. The ability to reproducibly extract quantitative information from our images is critical to research.

Discover in this webinar:

The importance of QC for scanners: calibration, reconstruction, and corrections.
PMOD’s software package for multimodality image analysis: data QC after loading or import, important aspects of segmentation and their effect on SUV, time-activity curves and kinetic modeling.
Important PET/SPECT image formats and their metadata.

Overcoming PROTAC Evaporation Bottlenecks

An evolving class of therapeutics has the potential to allow the design of new drugs targeting “undruggable” proteins which make up to 85% of the proteome. They are called PROteolysis TArgeting Chimeras (PROTACs). Yet, synthesis of PROTACs needs several evaporation steps, leading to bottlenecks in their workflow and a reduction in the speed of the drug development process. Many have researched PROTACs and the benefits they can offer to the drug discovery field. Further discussions have investigated the issues with their synthesis, and how this can be overcome.

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What is Digital Pathology?

The practice of digital pathology encompasses the sharing and management of digital imagery taken of microscope slides. The process, enabled by computer technology, allows scientists across the world to share and develop their knowledge surrounding the pathology of numerous diseases.

	Proteoforms in Drug Discovery Proteoforms are implicated in many types of diseases, ranging from Alzheimer’s disease to cancer. This article looks at proteoforms role in drug discovery.

	Digital Pathologies Use in Drug Development Digital pathology is facilitating data sharing between vast numbers of independent labs around the world, advancing drug discovery and development.

	What are Micro-Plates? Micro-plates, ‘microtiter plates’ or simply ‘microtiters’ are multi-well plates that can be sealed and employed in multiple applications.