Norepinephrine-stimulated HSCs secrete sFRP1 to promote HCC progression following chronic stress via augmentation of a Wnt16B/β-catenin positive feedback loop | Journal of Experimental & Clinical Cancer Research | Full Text

Norepinephrine-stimulated HSCs secrete sFRP1 to promote HCC progression following chronic stress via augmentation of a Wnt16B/β-catenin positive feedback loop | Journal of Experimental & Clinical Cancer Research | Full Text

Norepinephrine-stimulated HSCs secrete sFRP1 to promote HCC progression following chronic stress via augmentation of a Wnt16B/β-catenin positive feedback loop

Sustained adrenergic signaling secondary to chronic stress promotes cancer progression; however, the underlying mechanisms for this phenomenon remain unclear. Hepatocellular carcinoma (HCC) frequently develops...

Authors:Xia-Hui Lin, Hua-Hua Liu, Shu-Jung Hsu, Rui Zhang, Jie Chen, Jun Chen, Dong-Mei Gao, Jie-Feng Cui, Zheng-Gang Ren and Rong-Xin Chen

Citation:Journal of Experimental & Clinical Cancer Research 2020 39:64

Content type:Research

Published on: 15 April 2020

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