PERK/NRF2 and autophagy form a resistance mechanism against G9a inhibition in leukemia stem cells | Journal of Experimental & Clinical Cancer Research | Full Text

PERK/NRF2 and autophagy form a resistance mechanism against G9a inhibition in leukemia stem cells | Journal of Experimental & Clinical Cancer Research | Full Text

PERK/NRF2 and autophagy form a resistance mechanism against G9a inhibition in leukemia stem cells

The histone methyltransferase G9a has recently been identified as a potential target for epigenetic therapy of acute myeloid leukemia (AML). However, the effect of G9a inhibition on leukemia stem cells (LSCs),...

Authors:Ji Eun Jang, Ju-In Eom, Hoi-Kyung Jeung, Haerim Chung, Yu Ri Kim, Jin Seok Kim, June-Won Cheong and Yoo Hong Min

Citation:Journal of Experimental & Clinical Cancer Research 2020 39:66

Content type:Research

Published on: 15 April 2020

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