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ATP measurement as an objective method to measure environmental contamination in 9 hospitals in the Dutch/Belgian border area
The objective of this study was to determine the level of environmental contamination in hospitals in the Dutch/Belgian border area, using ATP measurements.Antimicrobial Resistance & Infection Control 2020 9:77Clinical characteristics and risk factors of polymicrobial Staphylococcus aureus bloodstream infections
Although Staphylococcus aureus bloodstream infections (SA-BSI) are a common and important infection, polymicrobial SA-BSI are infrequently reported. The aim of this study was to investigate the clinical character...Antimicrobial Resistance & Infection Control 2020 9:76The effect of a 5-year hand hygiene initiative based on the WHO multimodal hand hygiene improvement strategy: an interrupted time-series study
A World Health Organization (WHO) guideline-based multimodal hand hygiene (HH) initiative was introduced hospital-wide to a nonteaching Japanese hospital for 5 years. The objective of this study was to assess ...Antimicrobial Resistance & Infection Control 2020 9:75Early discontinuation of empirical antibiotic treatment in neutropenic patients with acute myeloid leukaemia and high-risk myelodysplastic syndrome
Current guidelines advocate empirical antibiotic treatment (EAT) in haematological patients with febrile neutropenia. However, the optimal duration of EAT is unknown. In 2011, we have introduced a protocol, pr...Antimicrobial Resistance & Infection Control 2020 9:74First detection of autochthonous extensively drug-resistant NDM-1 Pseudomonas aeruginosa ST235 from a patient with bloodstream infection in Italy, October 2019
Pseudomonas aeruginosa (PA) is one of the most common and serious causes of healthcare-associated bacteremia. The emergence and dissemination of multidrug-resistant (MDR) and extensively drug-resistant (XDR) PA s...Antimicrobial Resistance & Infection Control 2020 9:73A national survey of public awareness of antimicrobial resistance in Nigeria
One of the objectives of the Global Action Plan by the World Health Organization (WHO) to contain antimicrobial resistance (AMR), is to improve global awareness through effective communication and education. C...Antimicrobial Resistance & Infection Control 2020 9:72Acquisition of multidrug-resistant Enterobacterales during international travel: a systematic review of clinical and microbiological characteristics and meta-analyses of risk factors
International tourism increased from 25 million tourist arrivals in 1950 to over 1.3 billion in 2017. These travelers can be exposed to (multi) resistant microorganisms, may become colonized, and bring them ba...Antimicrobial Resistance & Infection Control 2020 9:71In vitro evaluation of double carbapenem and colistin combinations against OXA-48, NDM carbapenemase-producing colistin-resistant Klebsiella pneumoniae strains
Treatment of pandrug-resistant isolates often necessitates combination therapy. Checkerboard synergy and time-killing assay tests were performed to evaluate the benefits of a triple combination with meropenem,...Antimicrobial Resistance & Infection Control 2020 9:70Implementing a combined infection prevention and control with antimicrobial stewardship joint program to prevent caesarean section surgical site infections and antimicrobial resistance: a Tanzanian tertiary hospital experience
Surgical site infections are a leading cause of morbidity and mortality after caesarean section, especially in Low and Middle Income Countries. We hypothesized that a combined infection prevention and control ...Antimicrobial Resistance & Infection Control 2020 9:69- Antimicrobial Resistance & Infection Control 2020 9:68
Emergence of β-lactamase- and carbapenemase- producing Enterobacteriaceae at integrated fish farms
Epidemiological studies suggested that determinants for antibiotic resistance have originated in aquaculture. Recently, the integrated agriculture-aquaculture system has been implemented, where fish are raised...Antimicrobial Resistance & Infection Control 2020 9:67Predicting the occurrence of multidrug-resistant organism colonization or infection in ICU patients: development and validation of a novel multivariate prediction model
Multidrug-resistant organisms (MDROs) have emerged as an important cause of poor prognoses of patients in the intensive care unit (ICU). This study aimed to establish an easy-to-use nomogram for predicting the...Antimicrobial Resistance & Infection Control 2020 9:66Implementation of the WHO hand hygiene strategy in Faranah regional hospital, Guinea
Healthcare-associated infections are the most frequent adverse events in healthcare worldwide, with limited available evidence suggesting highest burden in resource-limited settings. Recent Ebola epidemics emp...Antimicrobial Resistance & Infection Control 2020 9:65Outbreak investigation of Serratia marcescens neurosurgical site infections associated with a contaminated shaving razors
Surgical site infection (SSI) is the most common healthcare-associated infection. We report an outbreak of neurosurgical site infections caused by Serratia marcescens after craniotomy in a tertiary care hospital.Antimicrobial Resistance & Infection Control 2020 9:64Point-prevalence survey of hospital acquired infections in three acute care hospitals in Northern Nigeria
Effective infection prevention and control strategies require reliable data describing the epidemiology of hospital acquired infections (HAIs), and this is currently lacking in Nigeria. The objective of this s...Antimicrobial Resistance & Infection Control 2020 9:63Screening for triazole resistance in clinically significant Aspergillus species; report from Pakistan
Burden of aspergillosis is reported to be significant from developing countries including those in South Asia. The estimated burden in Pakistan is also high on the background of tuberculosis and chronic lung d...Antimicrobial Resistance & Infection Control 2020 9:62Clinical impact of endemic NDM-producing Klebsiella pneumoniae in intensive care units of the national referral hospital in Jakarta, Indonesia
A prospective observational study was performed to assess the epidemiology and clinical impact of carbapenem-non-susceptible Klebsiella pneumoniae (CNKP) in intensive care units (ICUs) of the national referral ho...Antimicrobial Resistance & Infection Control 2020 9:61The potential negative impact of antibiotic pack on antibiotic stewardship in primary care in Switzerland: a modelling study
In Switzerland, oral antibiotics are dispensed in packs rather than by exact pill-count. We investigated whether available packs support compliance with recommended primary care treatment regimens for common i...Antimicrobial Resistance & Infection Control 2020 9:60Correction to: Implementation and impact of pediatric antimicrobial stewardship programs: a systematic scoping review
The original article [1] contains an error in Fig. 1 whereby the number of selected articles of the first box is incorrect.Antimicrobial Resistance & Infection Control 2020 9:59The original article was published in Antimicrobial Resistance & Infection Control 2020 9:3Bacteremia in critical care units at Bugando Medical Centre, Mwanza, Tanzania: the role of colonization and contaminated cots and mothers’ hands in cross-transmission of multidrug resistant Gram-negative bacteria
Multidrug resistance (MDR) is a major clinical problem in tertiary hospitals in Tanzania and jeopardizes the life of neonates in critical care units (CCUs). To better understand methods for prevention of MDR i...Antimicrobial Resistance & Infection Control 2020 9:58The great nursing brain drain and its effects on patient safety
The World Health Organization (WHO) has declared 2020 the “Year of the Nurse and Midwife”. On May 5th of this year, for the annual celebration of the SAVE LIVES: Clean Your Hands campaign, the WHO will focus o...Antimicrobial Resistance & Infection Control 2020 9:57The global prevalence of Daptomycin, Tigecycline, Quinupristin/Dalfopristin, and Linezolid-resistant Staphylococcus aureus and coagulase–negative staphylococci strains: a systematic review and meta-analysis
Methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative Staphylococcus (MRCoNS) are among the main causes of nosocomial infections, which have caused major problems in rece...Antimicrobial Resistance & Infection Control 2020 9:56Persuasive antimicrobial stewardship intervention in the context of a KPC outbreak: a controlled interrupted time series analysis
Antimicrobial resistance is a major public health threat. Antimicrobial stewardship (AMS) is one of the key strategies to overcome resistance, but robust evidence on the effect of specific interventions is lac...Antimicrobial Resistance & Infection Control 2020 9:55“Nurses and midwives: clean care is in your hands”: the 5th May 2020 World Health Organization SAVE LIVES: Clean Your Hands campaign
In honor of Florence Nightingale’s 200th birthday, the World Health Organization (WHO) has declared 2020 the “Year of the Nurse and Midwife”. On May 5th of this year, for the annual celebration of the SAVE LIV...Antimicrobial Resistance & Infection Control 2020 9:54Secular trend analysis of antibiotic utilisation in China’s hospitals 2011–2018, a retrospective analysis of procurement data
This study was aimed to explore the secular trends of antibiotic utilisation in China’s hospitals over an 8-year period.Antimicrobial Resistance & Infection Control 2020 9:53Emerging coexistence of three PMQR genes on a multiple resistance plasmid with a new surrounding genetic structure of qnrS2 in E. coli in China
Quinolones are commonly used for treatment of infections by bacteria of the Enterobacteriaceae family. However, the rising resistance to quinolones worldwide poses a major clinical and public health risk. This st...Antimicrobial Resistance & Infection Control 2020 9:52Sustained effects of a multimodal campaign aiming at hand hygiene improvement on compliance and healthcare-associated infections in a large gynaecology/obstetrics tertiary-care centre in Vietnam
Hung Vuong Hospital (HVH) is a 900-bed maternity hospital in Ho-Chi-Minh-City, Vietnam. Due to low compliance, a quasi-experimental, observational study was conducted with the aim to improve hand hygiene.Antimicrobial Resistance & Infection Control 2020 9:51Candida tropicalis is the most prevalent yeast species causing candidemia in Algeria: the urgent need for antifungal stewardship and infection control measures
Despite being associated with a high mortality and economic burden, data regarding candidemia are scant in Algeria. The aim of this study was to unveil the epidemiology of candidemia in Algeria, evaluate the a...Antimicrobial Resistance & Infection Control 2020 9:50Different screening frequencies of carbapenem-resistant Enterobacteriaceae in patients undergoing hematopoietic stem cell transplantation: which one is better?
A consensus has been reached that carbapenem-resistant Enterobacteriaceae (CRE) screening in immunosuppressed individuals can reduce the incidence of CRE bloodstream infection (BSI).Antimicrobial Resistance & Infection Control 2020 9:49Development of amoxicillin resistance in Escherichia coli after exposure to remnants of a non-related phagemid-containing E. coli: an exploratory study
To determine the effect of exposure to remnants of a phagemid-containing E. coli, killed by treatment with a propanol-based hand rub, on antimicrobial resistance in E. coli isolates.Antimicrobial Resistance & Infection Control 2020 9:48The prevalence and molecular mechanisms of mupirocin resistance in Staphylococcus aureus isolates from a Hospital in Cape Town, South Africa
Antimicrobial resistance is an increasingly serious problem in public health globally. Monitoring resistance levels within healthcare and community settings is critical to combat its ongoing increase. This stu...Antimicrobial Resistance & Infection Control 2020 9:47Antibiogram and beta-lactamase genes among cefotaxime resistant E. coli from wastewater treatment plant
The World Health Organization (WHO) recently classified Enterobacteriaceae resistance to third-generation cephalosporin into the group of pathogens with critical criteria for future research.Antimicrobial Resistance & Infection Control 2020 9:46Oral colonisation by antimicrobial-resistant Gram-negative bacteria among long-term care facility residents: prevalence, risk factors, and molecular epidemiology
For residents of long-term care facilities (LTCFs), antimicrobial-resistant bacteria (ARB) are a risk factor, yet their oral colonisation, potentially leading to aspiration pneumonia, remains unclear. This stu...Antimicrobial Resistance & Infection Control 2020 9:45Antimicrobial use and resistance in food-producing animals and the environment: an African perspective
The overuse of antimicrobials in food animals and the subsequent contamination of the environment have been associated with development and spread of antimicrobial resistance. This review presents information ...Antimicrobial Resistance & Infection Control 2020 9:37Prevalence, risk factors, phenotypic and molecular characteristics for Staphylococcus aureus carriage in community-based drug users in Guangzhou, China
Staphylococcus aureus (S. aureus), particularly methicillin-resistant Staphylococcus aureus (MRSA), remains the predominant cause of infections in drug users. This cross-sectional study aims to elucidate the prev...Antimicrobial Resistance & Infection Control 2020 9:44Molecular characterization of methicillin-resistant Staphylococcus aureus clinical strains from the endotracheal tubes of patients with nosocomial pneumonia
Among all cases of nosocomial pneumonia, Staphylococcus aureus is the second most prevalent pathogen (17.8%). In Europe, 29.9% of the isolates are oxacillin-resistant. The changing epidemiology of methicillin-res...Antimicrobial Resistance & Infection Control 2020 9:43Infection control link nurse programs in Dutch acute care hospitals; a mixed-methods study
Infection control link nurse programs show considerable variation. We report how Dutch link nurse programs are organized, how they progress, and how contextual factors may play a role in the execution of these...Antimicrobial Resistance & Infection Control 2020 9:42Prevalence and molecular characterizations of Staphylococcus aureus nasal colonization among patients in pediatric intensive care units in Taiwan
Nasal colonization of Staphylococcus aureus is a risk factor for the pathogen transmission and the development of infections. Limited information is available on the prevalence and molecular characteristics of S....Antimicrobial Resistance & Infection Control 2020 9:41
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