The analysis identified two places, one on chromosome 3 and covers a cluster of six genes with potentially relevant functions such as a protein known to interact with angiotensin converting enzyme 2 (ACE2). The other association signal popped up on chromosome 9, right over the area of the genome that determines ABO blood type.
Genomewide Association Study of Severe Covid-19 with Respiratory Failure
D Ellinghaus et al, NEJM, June 17, 2020
D Ellinghaus et al, NEJM, June 17, 2020
We conducted a genomewide association study involving 1980 patients with Covid-19 and severe disease (defined as respiratory failure) at seven hospitals. We identified a 3p21.31 gene cluster as a genetic susceptibility locus in patients with Covid-19 with respiratory failure and confirmed a potential involvement of the ABO blood-group system.
COVID-19 Update: Blood Type Link, Comorbidities and Mortality
M McNamara, Medscape, June 17, 2020
M McNamara, Medscape, June 17, 2020
COVID-19 and Blood Type: 'May Be Something Here'- Evidence is mounting that people with Type A blood could be at higher risk for COVID-19 infection and mortality, according to three recent studies. At the same time, Type O blood may be somewhat protective.
Digital Contact Tracing Using IP Colocation
M Malloy et al, ARXIV, June 16, 2020
M Malloy et al, ARXIV, June 16, 2020
Genome-wide mapping of therapeutically-relevant SARS-CoV-2 RNA structures
L Manfredonia et al, BIORXIV, June 15, 2020
L Manfredonia et al, BIORXIV, June 15, 2020
Proteomics Uncovers Immunosuppression in COVID-19 Patients with Long Disease Course
S Tang et al, MEDRXIV, June 17, 2020
S Tang et al, MEDRXIV, June 17, 2020
FAST: a Flexible, Accurate and Speedy Test Strategy for COVID-19
L Fang et al, MEDRXIV, June 16, 2020
L Fang et al, MEDRXIV, June 16, 2020
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