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Sentinel headache as a warning symptom of ischemic stroke
There are no previous controlled studies of sentinel headache in ischemic stroke. The purpose of the present study was to evaluate the presence of such headache, its characteristics and possible risk factors a...21:70The Journal of Headache and Pain 2020Multidimensional assessment of the effects of erenumab in chronic migraine patients with previous unsuccessful preventive treatments: a comprehensive real-world experience
erenumab was safe and effective in clinical trials for the prevention of migraine. However, real-life data are still lacking. Here we report the clinical experience from an Italian real-world setting using ere...21:69The Journal of Headache and Pain 2020Impact of migraine on workplace productivity and monetary loss: a study of employees in banking sector in Malaysia
Productivity and monetary loss due to migraine in the workplace may be substantial. This study aimed to determine the impact of migraine on productivity and monetary lost among employees in the banking sectors...21:68The Journal of Headache and Pain 2020High sensitivity C-reactive protein and risk of migraine in a 11-year follow-up with data from the Nord-Trøndelag health surveys 2006–2008 and 2017–2019
Several previous studies have reported a cross-sectional association between elevated high sensitivity C-reactive protein (hs-CRP) and migraine. The aim of this population-based follow-up study was to investig...21:67The Journal of Headache and Pain 2020Short-term efficacy and safety of lasmiditan, a novel 5-HT1F receptor agonist, for the acute treatment of migraine: a systematic review and meta-analysis
Migraine has been recognized as one of common diseases in the world whose current treatment options are not ideal. Lasmiditan, an oral 5-hydroxytryptamine (HT)1F receptor agonist, appears more promising for the a...21:66The Journal of Headache and Pain 2020The fifth cranial nerve in headaches
The fifth cranial nerve is the common denominator for many headaches and facial pain pathologies currently known. Projecting from the trigeminal ganglion, in a bipolar manner, it connects to the brainstem and ...21:65The Journal of Headache and Pain 2020Genetics of migraine aura: an update
Migraine is a common brain disorder with a large genetic component. Of the two main migraine types, migraine with aura and migraine without aura, the genetic underpinning in the former is least understood. Giv...21:64The Journal of Headache and Pain 2020On the utility of the trail making test in migraine with and without aura: a meta-analysis
This meta-analytical review assesses the utility of the Trail Making Test (TMT), versions A and B, in detecting migraine-related cognitive deficits. A comprehensive literature search was performed in two elect...21:63The Journal of Headache and Pain 2020Efficacy, tolerability, and safety of erenumab for the preventive treatment of persistent post-traumatic headache attributed to mild traumatic brain injury: an open-label study
Calcitonin gene-related peptide (CGRP) has recently been implicated in the pathogenesis of post-traumatic headache (PTH), which raises the prospect for therapeutic use of monoclonal antibodies targeting CGRP o...21:62The Journal of Headache and Pain 2020A prospective real-world analysis of erenumab in refractory chronic migraine
Clinical trials have shown the safety and clinical superiority of erenumab compared to placebo in chronic migraine (CM). The aim of this analysis is to evaluate the effectiveness and tolerability of erenumab i...21:61The Journal of Headache and Pain 2020The applicability of web-based solutions in headache epidemiology research
Epidemiological research of headache is vital but resource consuming prerequisite for evidence-based development in the field. Rapid evolution of information technology may provide new opportunities for popula...21:60The Journal of Headache and Pain 2020Microstructural changes in the trigeminal nerve of patients with episodic migraine assessed using magnetic resonance imaging
There is histological evidence of microstructural changes in the zygomaticotemporal branch of the trigeminal nerve in migraineurs. This raises the possibility that altered trigeminal nerve properties contribut...21:59The Journal of Headache and Pain 2020The impact of remission and coexisting migraine on anxiety and depression in cluster headache
Our aim was to investigate the relationship between coexisting cluster headache (CH) and migraine with anxiety and depression during active cluster bouts, and how symptoms change during remission.21:58The Journal of Headache and Pain 2020Volume of the rectus capitis posterior minor muscle in migraine patients: a cross-sectional structural MRI study
Neck pain in migraine patients is very prevalent between and during migraine attacks, but the underlying mechanism behind neck pain in migraine is unknown. The neck muscle rectus capitis posterior minor muscle...21:57The Journal of Headache and Pain 2020Subdiagnosis, but not presence of vestibular symptoms, predicts balance impairment in migraine patients – a cross sectional study
Vestibular symptoms and balance changes are common in patients with migraine, especially in the ones with aura and chronic migraine. However, it is not known if the balance changes are determined by the presen...21:56The Journal of Headache and Pain 2020Persistent post-traumatic headache: a migrainous loop or not? The clinical evidence
Headache is a common complication of traumatic brain injury. The International Headache Society defines post-traumatic headache as a secondary headache attributed to trauma or injury to the head that develops ...21:55The Journal of Headache and Pain 2020Persistence of pregabalin treatment in Taiwan: a nation-wide population-based study
Pregabalin is approved for the treatment of neuropathic pain, fibromyalgia, and seizure disorders, although the pivotal trials were mostly carried out in Europe or North America. The prescribing patterns among...21:54The Journal of Headache and Pain 2020Migraine treatment and healthcare costs: retrospective analysis of the China Health Insurance Research Association (CHIRA) database
Adult migraine remains underdiagnosed and undertreated, despite significant negative effects on physical and emotional functioning. Information on prescribing patterns and treatment costs of migraine in China ...21:53The Journal of Headache and Pain 2020Pain rates in general population for the period 1991–2015 and 10-years prediction: results from a multi-continent age-period-cohort analysis
Pain is a common symptom, often associated with neurological and musculoskeletal conditions, and experienced especially by females and by older people. The aims of this study are to evaluate the temporal varia...21:52The Journal of Headache and Pain 2020- 21(Suppl 1):43The Journal of Headache and Pain 2020
Jealousy in women with migraine: a cross-sectional case-control study
Estrogen influences susceptibility to migraine attacks and it has been suggested to affect jealousy in romantic relationships in women. Therefore, we hypothesized that migraine women may be more jealous.21:51The Journal of Headache and Pain 2020Lost productivity associated with headache and depression: a quality improvement project identifying a patient population at risk
This quality improvement project was implemented in order to highlight the association between headache, mTBI and depression on lost productivity and resource utilization.21:50The Journal of Headache and Pain 2020Use of outpatient medical care by headache patients in Germany: a population-based cross-sectional study
Headache sufferers in need of professional health care often do not utilize the care available, and factors influencing headache-specific physician consultation are not yet understood. Objectives of this study...21:49The Journal of Headache and Pain 2020Sensory processing patterns affect headache severity among adolescents with migraine
To evaluate the relationship between pain catastrophizing level, sensory processing patterns, and headache severity among adolescents with episodic migraine.21:48The Journal of Headache and Pain 2020Disrupted functional connectivity between sub-regions in the sensorimotor areas and cortex in migraine without aura
Migraine is a severe and disabling brain disorder, and the exact neurological mechanisms remain unclear. Migraineurs have altered pain perception, and headache attacks disrupt their sensory information process...21:47The Journal of Headache and Pain 2020Increased risk of tinnitus following a trigeminal neuralgia diagnosis: a one-year follow-up study
Tinnitus due to hyperactivity across neuronal ensembles along the auditory pathway is reported. We hypothesized that trigeminal neuralgia patients may subsequently suffer from tinnitus. Using nationwide, popul...21:46The Journal of Headache and Pain 2020Predictors of pain in general ageing populations: results from a multi-country analysis based on ATHLOS harmonized database
Pain is a common symptom, often associated with neurological and musculoskeletal conditions, and experienced especially by females and by older people, and with increasing trends in general populations. Differ...21:45The Journal of Headache and Pain 2020Direct and indirect costs of cluster headache: a prospective analysis in a tertiary level headache centre
Cluster headache (CH) is the most frequent trigemino-autonomic cephalgia. CH can manifest as episodic (ECH) or chronic cluster headache (CCH) causing significant burden of disease and requiring attack therapy ...21:44The Journal of Headache and Pain 2020From transformation to chronification of migraine: pathophysiological and clinical aspects
Chronic migraine is a neurological disorder characterized by 15 or more headache days per month of which at least 8 days show typical migraine features. The process that describes the development from episodic...21:42The Journal of Headache and Pain 2020A global real-world assessment of the impact on health-related quality of life and work productivity of migraine in patients with insufficient versus good response to triptan medication
Migraine is a chronic, disabling neurological disease characterized by moderate-to-severe headache pain with other symptoms, including nausea, vomiting, and photophobia. Triptans, while generally effective, ar...21:41The Journal of Headache and Pain 2020Sustained response to onabotulinumtoxin A in patients with chronic migraine: real-life data
Treatment with onabotulinumtoxin A (BT-A) is safe and effective for chronic migraine (CM). Several studies assessed possible predictors of response to treatment with BT-A, but there is little knowledge on the ...21:40The Journal of Headache and Pain 2020Brain morphologic abnormalities in migraine patients: an observational study
Migraine is a common neurological disorder characterized by a complex physiopathology. We assessed brain morphologic differences in migraine and the possible pathogenetic mechanism underlying this disease.21:39The Journal of Headache and Pain 2020Headache medication and the COVID-19 pandemic
The world is currently dominated by the Corona Virus Disease 2019 (COVID-19) pandemic. Besides the obvious concerns about limitation of virus spread and providing the best possible care to infected patients, a...21:38The Journal of Headache and Pain 2020Prevalence of familial cluster headache: a systematic review and meta-analysis
The population rate of familial cluster headache (CH) has been reported to be as high as 20% however this varies considerably across studies. To obtain a true estimate of family history in CH, we conducted a s...21:37The Journal of Headache and Pain 2020- 21:36The Journal of Headache and Pain 2020
Neurotransmitter and tryptophan metabolite concentration changes in the complete Freund’s adjuvant model of orofacial pain
The neurochemical background of the evolution of headache disorders, still remains partially undiscovered. Accordingly, our aim was to further explore the neurochemical profile of Complete Freund’s adjuvant (C...21:35The Journal of Headache and Pain 2020Short-latency afferent inhibition and somato-sensory evoked potentials during the migraine cycle: surrogate markers of a cycling cholinergic thalamo-cortical drive?
Short-latency afferent inhibition (SAI) consists of motor cortex inhibition induced by sensory afferents and depends on the excitatory effect of cholinergic thalamocortical projections on inhibitory GABAergic ...21:34The Journal of Headache and Pain 2020Clinical correlates of insomnia in patients with persistent post-traumatic headache compared with migraine
Close associations between insomnia with other clinical factors have been identified in migraine, but there have been few studies investigating associations between insomnia and clinical factors in patients wi...21:33The Journal of Headache and Pain 2020Real-life data on the efficacy and safety of erenumab in the Abruzzo region, central Italy
We aimed to assess the efficacy and safety of erenumab, a fully human monoclonal antibody inhibiting the calcitonin gene-related peptide receptor (CGRPr), for the prevention of migraine in a real-life setting.21:32The Journal of Headache and Pain 2020
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