C9orf72-associated SMCR8 protein binds in the ubiquitin pathway and with proteins linked with neurological disease | Acta Neuropathologica Communications | Full Text

C9orf72-associated SMCR8 protein binds in the ubiquitin pathway and with proteins linked with neurological disease | Acta Neuropathologica Communications | Full Text

C9orf72-associated SMCR8 protein binds in the ubiquitin pathway and with proteins linked with neurological disease

A pathogenic GGGCCC hexanucleotide expansion in the first intron/promoter region of the C9orf72 gene is the most common mutation associated with amyotrophic lateral sclerosis (ALS). The C9orf72 gene product forms...

Authors:John L. Goodier, Alisha O. Soares, Gavin C. Pereira, Lauren R. DeVine, Laura Sanchez, Robert N. Cole and Jose Luis García-Pérez

Citation:Acta Neuropathologica Communications 2020 8:110

Content type:Research

 

Published on: 16 July 2020

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