CSF levels of the BACE1 substrate NRG1 correlate with cognition in Alzheimer’s disease | Alzheimer's Research & Therapy | Full Text

CSF levels of the BACE1 substrate NRG1 correlate with cognition in Alzheimer’s disease | Alzheimer's Research & Therapy | Full Text

CSF levels of the BACE1 substrate NRG1 correlate with cognition in Alzheimer’s disease

The presynaptic protein neuregulin1 (NRG1) is cleaved by beta-site APP cleaving enzyme 1 (BACE1) in a similar way as amyloid precursor protein (APP) NRG1 can activate post-synaptic receptor tyrosine-protein ki...

Authors:François Mouton-Liger, Julien Dumurgier, Emmanuel Cognat, Claire Hourregue, Henrik Zetterberg, Hugo Vanderstichele, Eugeen Vanmechelen, Elodie Bouaziz-Amar, Kaj Blennow, Jacques Hugon and Claire Paquet

Citation:Alzheimer's Research & Therapy 2020 12:88

Content type:Research

 

Published on: 20 July 2020

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