Colorectal cancer || Public Health Genomics Knowledge Base (v1.2)

Public Health Genomics Knowledge Base (v1.2)






Last Updated: Sep 01, 2016

• Two subtypes of colorectal tumor with distinct molecular features in familial adenomatous polyposis.
  Takane Kiyoko, et al. Oncotarget 2016 8
• Colorectal cancer in the very young: a comparative study of tumor markers, pathology and survival in early onset and adult onset patients.
  Khan Sajid A, et al. Journal of pediatric surgery 2016 8
• High serum levels of interleukin-6 in patients with advanced or metastatic colorectal cancer: the effect on the outcome and the response to chemotherapy plus bevacizumab.
  Hara Masayasu, et al. Surgery today 2016 8
• Colonoscopy uptake for high-risk individuals with a family history of colorectal neoplasia: A multicenter, randomized trial of tailored counseling versus standard information.
  Ingrand Isabelle et al. Medicine 2016 Aug 95(33) e4303
• Familial colorectal cancer: Patient assessment, surveillance and surgical management.
  Kennelly R P et al. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2016 Jul
• The impact of receiving predictive genetic information about Lynch syndrome on individual colonoscopy and smoking behaviours.
  Kim Joanne Soo-Min et al. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2016 Aug
• KRAS, BRAF oncogene mutations and tissue specific promoter hypermethylation of tumor suppressor SFRP2, DAPK1, MGMT, HIC1 and p16 genes in colorectal cancer patients.
  Bagci Binnur, et al. Cancer biomarkers : section A of Disease markers 2016 6 (2) 133-43
• Low Gene Dosage of Cdc42 Is Not Associated with Protein Dysfunction in Patients with Colorectal Cancer.
  González-Quiroz Matías, et al. DNA and cell biology 2016 8
• Carrier molecules and extraction of circulating tumor DNA for next generation sequencing in colorectal cancer.
  Beránek Martin, et al. Acta medica (Hradec Kra?love?) / Universitas Carolina, Facultas Medica Hradec Kra?love? 2016 0 (2) 54-8
• Epigenetic Homogeneity Within Colorectal Tumors Predicts Shorter Relapse-free and Overall Survival Times for Patients With Loco-regional Cancer.
  Martínez-Cardús Anna, et al. Gastroenterology 2016 8
• A Prospective Six Sigma Quality Improvement Trial to Optimize Universal Screening for Genetic Syndrome Among Patients With Young-Onset Colorectal Cancer.
  Dineen Sean et al. Journal of the National Comprehensive Cancer Network : JNCCN 2015 Jul 13(7) 865-72
• A state-wide population-based program for detection of lynch syndrome based upon immunohistochemical and molecular testing of colorectal tumours.
  Schofield Lyn et al. Familial cancer 2012 Mar 11(1) 1-6
• Advances in Hereditary Colorectal and Pancreatic Cancers.
  Underhill Meghan L et al. Clinical therapeutics 2016 Jul 38(7) 1600-21
• Fourfold increased detection of Lynch syndrome by raising age limit for tumour genetic testing from 50 to 70 years is cost-effective.
  Sie A S et al. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2014 Oct 25(10) 2001-7
• Implementation of screening colonoscopy amongst first- degree relatives of patients with colorectal cancer in Turkey: a cross-sectional questionnaire based survey.
  Adakan Yesim et al. Asian Pacific journal of cancer prevention : APJCP 2014 15(14) 5523-8

• CDC Information (8)
• CDC-Authored Pub (13)

• Human (57)
• Pathogen (5)

• Human (4040)
• Pathogen (0)

• Human (231)
• Pathogen (0)

• Guidelines (16)
• Tier Table (19)
• Synthesis (58)

• Huamn (83)
• Pathogen (0)

Relevant Resources

• Cancer Genomics and Epidemiology Navigator (CGEN)
• Genetics and Genomics Competencies Center (G2C2)
• NIH Genetic Testing Registry
• NIH MedGen Database
• Online Mendelian Inheritance in Man (OMIM)
• PharmGKB