Daphnée Lamarche & Dr. Jennie Johnstone
Daphnée Lamarche is a PhD Candidate in the Department of Biochemistry and Biomedical Sciences at McMaster University. Her research focuses on improving our understanding of complex respiratory infections using microbiome analysis, genomics and by investigating host-pathogens interactions.
Dr. Jennie Johnstone is an Infectious Diseases physician and Epidemiologist at Public Health Ontario and Sinai Health System in Toronto, Ontario. Her research focus is the prevention and control of infections in the healthcare setting.
Dr. Jennie Johnstone is an Infectious Diseases physician and Epidemiologist at Public Health Ontario and Sinai Health System in Toronto, Ontario. Her research focus is the prevention and control of infections in the healthcare setting.
How does critical illness impact our microbiomes?
New research published in Respiratory Research examined microbiota in lung, stomach and fecal samples of critically ill patients, finding reduced microbial diversity to reflect high illness severity and an association with mortality. Here to talk about this and other findings of their study are two of the authors, Daphnée Lamarche and Dr. Jennie Johnstone.
Scanning electron micrograph (SEM) of various bacteria found in a sample of human faeces.
© Steve Gschmeissner / Science Photo Library
Our bodies harbour trillions of bacterial cells called the microbiota. In healthy people, distinct communities of microbiota are found at different body sites. These organisms confer beneficial advantages to our bodies such as metabolism (breaking down complex polysaccharides and vitamins synthesis), resistance to infection and immune homeostasis. In return we provide an ecological niche and nutrients to the microbes.
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