Proteomics reveals a therapeutic vulnerability via the combined blockade of APE1 and autophagy in lung cancer A549 cells | BMC Cancer | Full Text

Proteomics reveals a therapeutic vulnerability via the combined blockade of APE1 and autophagy in lung cancer A549 cells | BMC Cancer | Full Text

Proteomics reveals a therapeutic vulnerability via the combined blockade of APE1 and autophagy in lung cancer A549 cells

Drug resistance is a major cause of therapeutic failure that is often associated with elevated autophagy and apurinic/apyrimidinic endonuclease 1 (APE1) expression. Herein, we investigated the role of APE1 and...

Authors:Shu-Ting Pan, Ji Zhou, Fang Yang, Shu-Feng Zhou and Tao Ren

Citation:BMC Cancer 2020 20:634

Content type:Research article

 

Published on: 8 July 2020

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