sábado, 4 de julio de 2020

Radiation Oncology | Articles

Radiation Oncology | Articles



  1. The objectives of this study were to determine the objective effective response rate, survival, and safety of radiotherapy combined with gefitinib in patients with locally advanced non-small cell lung cancer (...
    Authors:Zhixue Fu, Xu Yang, Wenqing Wang, Lei Deng, Tao Zhang, Nan Bi, Xiaozhen Wang, Dongfu Chen, Zongmei Zhou, Luhua Wang and Jun Liang
    Citation:Radiation Oncology 2020 15:155
    Content type:Research
     
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  2. Healthcare workers occupationally exposed to 18F-FDG cannot wear protective equipment, such as lead aprons, since the interaction between high energy radiation (511 keV) and metal increases the dose of radiation ...
    Authors:Nilson Benedito Lopes, Igor Vivian Almeida, Pedro Henrique Silvestre Lopes and Veronica Elisa Pimenta Vicentini
    Citation:Radiation Oncology 2020 15:154
    Content type:Research
     
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  3. Even though frequent, it is not known how HIV infection and treatment impact in the consolidation by radiotherapy of non-Hodgkin diffuse large B-cell lymphomas (DBCL). This article aim to assess that differenc...
    Authors:Carolina Trindade Mello Medici, Geovanne Pedro Mauro, Lucas Coelho Casimiro and Eduardo Weltman
    Citation:Radiation Oncology 2020 15:153
    Content type:Research
     
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  4. Internal Target Volume (ITV) is one of the most common strategies to passively manage tumour motion in Radiotherapy (RT).
    Authors:Davide Cusumano, Jennifer Dhont, Luca Boldrini, Giuditta Chiloiro, Angela Romano, Claudio Votta, Silvia Longo, Lorenzo Placidi, Luigi Azario, Marco De Spirito, Dirk Verellen and Vincenzo Valentini
    Citation:Radiation Oncology 2020 15:152
    Content type:Research
     
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  5. Chemoradiotherapy remains the standard of care for locally advanced rectal cancer. Efforts to intensify treatment and increase response rates have yet to yield practice changing results due to increased toxici...
    Authors:Séan M. O’Cathail, Steven Davis, Jane Holmes, Richard Brown, Kerry Fisher, Leonard Seymour, Richard Adams, James Good, David Sebag-Montefiore, Tim Maughan and Maria A. Hawkins
    Citation:Radiation Oncology 2020 15:151
    Content type:Study protocol
     
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  6. Retrospective analysis of volumetric modulated arc therapy treatment plans to investigate qualitative, possible, clinical consequences of the use of AAA versus AXB in nasopharyngeal cancer (NPC) cases.
    Authors:Antonella Bufacchi, Orietta Caspiani, Giulia Rambaldi, Luca Marmiroli, Giuseppe Giovinazzo and Mattia Polsoni
    Citation:Radiation Oncology 2020 15:150
    Content type:Research
     
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  7. Optimal alignment is of utmost importance when treating pediatric patients with craniospinal irradiation (CSI), especially with regards to field junctions and multiple isocenters and techniques applying high d...
    Authors:Daniel Gram, André Haraldsson, N. Patrik Brodin, Karsten Nysom, Thomas Björk-Eriksson and Per Munck af Rosenschöld
    Citation:Radiation Oncology 2020 15:149
    Content type:Research
     
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  8. Loco-regional and distant failure are common in inoperable stage III non small-cell lung cancer (NSCLC) after chemoradiotherapy (CRT). However, there is limited real-world data on failure pattern, patient prog...
    Authors:Julian Taugner, Chukwuka Eze, Lukas Käsmann, Olarn Roengvoraphoj, Kathrin Gennen, Monika Karin, Oleg Petrukhnov, Amanda Tufman, Claus Belka and Farkhad Manapov
    Citation:Radiation Oncology 2020 15:148
    Content type:Research
     
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  9. There is a lack of consensus concerning the definition of re-irradiation and re-irradiation volumes in head and neck cancer (HNC). The aim of the present study is to introduce a more strict definition of the r...
    Authors:Anna Embring, Eva Onjukka, Claes Mercke, Ingmar Lax, Anders Berglund, Sara Bornedal, Berit Wennberg and Signe Friesland
    Citation:Radiation Oncology 2020 15:147
    Content type:Research
     
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  10. At present, the treatment of recurrent glioblastoma is extremely challenging. In this study, we used a novel three-dimensional non-coplanar template (3DNPT) combined with open MR to guide 125I seed implantation f...
    Authors:Xiangmeng He, Ming Liu, Menglong Zhang, Roberto Blanco Sequeiros, Yujun Xu, Ligang Wang, Chao Liu, Qingwen Wang, Kai Zhang and Chengli Li
    Citation:Radiation Oncology 2020 15:146
    Content type:Research
     
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  11. Glioblastoma multiforme (GBM) has a poor prognosis despite a multi modal treatment that includes normofractionated radiotherapy. So, various hypofractionated alternatives to normofractionated RT have been test...
    Authors:Jane-Chloe Trone, Alexis Vallard, Sandrine Sotton, Majed Ben Mrad, Omar Jmour, Nicolas Magné, Benjamin Pommier, Silvy Laporte and Edouard Ollier
    Citation:Radiation Oncology 2020 15:145
    Content type:Review
     
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  12. Desmoid-type fibromatosis is a rare, potentially locally aggressive disease. Herein we present our experience in the treatment with radiotherapy.
    Authors:K. Seidensaal, S. B. Harrabi, F. Weykamp, K. Herfarth, T. Welzel, G. Mechtersheimer, B. Lehner, M. Schneider, S. Fröhling, G. Egerer, J. Debus and M. Uhl
    Citation:Radiation Oncology 2020 15:143
    Content type:Research
     
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  13. Radiation-induced choanal stenosis (RICS) severely decreases life quality of patients with nasopharyngeal carcinoma (NPC) and originates from nasal mucositis, which depends on radiation dose. This self-control...
    Authors:Hui Chang, Kai Chen, Ya-lan Tao, Fei Han, Wei-jun Ye and Yuan-hong Gao
    Citation:Radiation Oncology 2020 15:142
    Content type:Research
     
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  14. Murine models are among the most common type of preclinical animal models used to study the human condition, but a wide selection of different mice is currently in use with these differences potentially compro...
    Authors:Andrew J. Boria and Carlos J. Perez-Torres
    Citation:Radiation Oncology 2020 15:141
    Content type:Research
     
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  15. To examine, if a shift in indications for radiotherapy is to be expected in the context of the COVID-19 pandemic, the database Pubmed was searched for multidisciplinary or surgical expert recommendations on th...
    Authors:Dirk Vordermark
    Citation:Radiation Oncology 2020 15:140
    Content type:Short report
     
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  16. Immunotherapy has paved the way for new therapeutic opportunities in cancer but has failed to show any efficacy in Pancreatic Adenocarcinoma (PDAC), and its therapeutic role remains unclear. The objective of t...
    Authors:Saber Amin, Michael Baine, Jane Meza, Morshed Alam and Chi Lin
    Citation:Radiation Oncology 2020 15:139
    Content type:Research
     
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  17. Developments in the field of proton beam therapy (PBT) have recently crossed the tipping point wherein the modality is now more versatile than ever before, with possibilities and likely indications expanding r...
    Authors:Srinivas Chilukuri, Pankaj Kumar Panda and Rakesh Jalali
    Citation:Radiation Oncology 2020 15:138
    Content type:Commentary
     
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  18. Circulating tumor cells (CTCs) are an established prognostic marker in castration-resistant prostate cancer but have received little attention in localized high-risk disease. We studied the detection rate of C...
    Authors:Almudena Zapatero, Antonio Gómez-Caamaño, María Ángeles Cabeza Rodriguez, Laura Muinelo-Romay, Carmen Martin de Vidales, Alicia Abalo, Patricia Calvo Crespo, Luis Leon Mateos, Carlos Olivier and Lorena Vega Vega Piris
    Citation:Radiation Oncology 2020 15:137
    Content type:Research
     
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  19. To validate the Radiation Therapy Oncology Group (RTOG) and European Society for Radiotherapy and Oncology (ESTRO) breast cancer nodal clinical target volumes (CTVs) and to investigate the Radiotherapy Compara...
    Authors:Laura Beaton, Luminita Nica, Scott Tyldesley, Kenny Sek, Gareth Ayre, Maria Aparicio, Lovedeep Gondara, Caroline Speers and Alan Nichol
    Citation:Radiation Oncology 2020 15:136
    Content type:Research
     
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  20. Melanoma patients frequently develop brain metastases. The most widely used score to predict survival is the molGPA based on a mixed treatment of stereotactic radiotherapy (SRT) and whole brain radiotherapy (W...
    Authors:Jana Schaule, Stephanie G. C. Kroeze, Oliver Blanck, Susanne Stera, Klaus H. Kahl, Falk Roeder, Stephanie E. Combs, David Kaul, An Claes, Markus M. Schymalla, Sonja Adebahr, Franziska Eckert, Fabian Lohaus, Nasrin Abbasi-Senger, Guido Henke, Marcella Szuecs…
    Citation:Radiation Oncology 2020 15:135
    Content type:Research
     
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  21. Fatigue is one of the most common and distressing side-effects of breast cancer radiotherapy. According to current guidelines, accelerated partial breast irradiation (APBI) may be considered as an alternative ...
    Authors:Tobias Forster, Cornelia Jäkel, Sati Akbaba, David Krug, Robert Krempien, Matthias Uhl, Matthias Felix Häfner, Laila König, Stefan Alexander Koerber, Semi Harrabi, Denise Bernhardt, Rouven Behnisch, Johannes Krisam, Andre Hennigs, Christof Sohn, Jörg Heil…
    Citation:Radiation Oncology 2020 15:134
    Content type:Study protocol
     
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  22. Endoscopic resection is widely used as an effective treatment for superficial esophageal cancer. However, the risk of lymph node metastasis increases in cases of muscularis mucosae or deeper invasion, for whic...
    Authors:Ikuno Nishibuchi, Yuji Murakami, Yoshinori Adachi, Nobuki Imano, Yuki Takeuchi, Ippei Tkahashi, Tomoki Kimura, Yuji Urabe, Shiro Oka, Shinji Tanaka and Yasushi Nagata
    Citation:Radiation Oncology 2020 15:133
    Content type:Research
     
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  23. The evaluation of circulating tumour DNA (ctDNA) from clinical blood samples, liquid biopsy, offers several diagnostic advantages compared with traditional tissue biopsy, such as shorter processing time, reduc...
    Authors:G. M. Walls, L. McConnell, J. McAleese, P. Murray, T. B. Lynch, K. Savage, G. G. Hanna and D. Gonzalez de Castro
    Citation:Radiation Oncology 2020 15:132
    Content type:Research
     
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  24. Radiosensitivity is limited in cervical cancer (CC) patients due to acquired radiation resistance. In our previous studies, we found that immediate-early response 5 (IER5) is upregulated in CC cells upon radia...
    Authors:Jing-Jie Zheng, Yue He, Yang Liu, Feng-Shuang Li, Zhen Cui, Xiao-Meng Du, Chun-Peng Wang and Yu-Mei Wu
    Citation:Radiation Oncology 2020 15:131
    Content type:Research
     
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  25. PTV concept is presumed to introduce excessive and inconsistent GTV dose in lung stereotactic body radiotherapy (SBRT). That GTV median dose prescription (D50) and robust optimization are viable PTV–free solution...
    Authors:Ronnie Wing King Leung, Mark Ka Heng Chan, Chi-Leung Chiang, Matthew Wong and Oliver Blanck
    Citation:Radiation Oncology 2020 15:130
    Content type:Research
     
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  26. The targeting accuracy of proton therapy (PT) for moving soft-tissue tumours is expected to greatly improve by real-time magnetic resonance imaging (MRI) guidance. The integration of MRI and PT at the treatmen...
    Authors:Aswin Hoffmann, Bradley Oborn, Maryam Moteabbed, Susu Yan, Thomas Bortfeld, Antje Knopf, Herman Fuchs, Dietmar Georg, Joao Seco, Maria Francesca Spadea, Oliver Jäkel, Christopher Kurz and Katia Parodi
    Citation:Radiation Oncology 2020 15:129
    Content type:Review
     
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  27. Hypofractionated-SRS (HF-SRS) may allow for improved local control and a reduced risk of radiation necrosis compared to single-fraction-SRS (SF-SRS). However, data comparing these two treatment approaches are ...
    Authors:Jill S. Remick, Emily Kowalski, Rahul Khairnar, Kai Sun, Emily Morse, Hua-Ren R. Cherng, Yannick Poirier, Narottam Lamichhane, Stewart J. Becker, Shifeng Chen, Akshar N. Patel, Young Kwok, Elizabeth Nichols, Pranshu Mohindra, Graeme F. Woodworth, William F. Regine…
    Citation:Radiation Oncology 2020 15:128
    Content type:Research
     
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  28. Carbon-ion radiotherapy (CIRT) for prostate cancer was initiated at Kanagawa Cancer Center in 2015. The present study analyzed the preliminary clinical outcomes of CIRT for prostate cancer.
    Authors:Yosuke Takakusagi, Hiroyuki Katoh, Kio Kano, Wataru Anno, Keisuke Tsuchida, Nobutaka Mizoguchi, Itsuko Serizawa, Daisaku Yoshida and Tadashi Kamada
    Citation:Radiation Oncology 2020 15:127
    Content type:Research
     
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  29. To evaluate the impact of primary tumor radiotherapy on survival in patients with unresectable metastatic rectal or rectosigmoid cancer.
    Authors:Gang Wang, Wenling Wang, Haijie Jin, Hongmin Dong, Weiwei Chen, Xiaokai Li, Guodong Li and Leilei Li
    Citation:Radiation Oncology 2020 15:126
    Content type:Research
     
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  30. Anal cancer is a rare disease, which might be the reason for the “one size fits all” approach still used for radiotherapy target contouring. To refine and individualize future guidelines, detailed and contempo...
    Authors:Martin P. Nilsson, Erik D. Nilsson, Anders Johnsson, Otilia Leon, Adalsteinn Gunnlaugsson and Jonas Scherman
    Citation:Radiation Oncology 2020 15:125
    Content type:Research
     
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  31. To investigate the loco-regional progression-free survival (LPFS) of intensity-modulated radiotherapy (IMRT) with different fraction sizes for locally advanced non-small-cell lung cancer (LANSCLC), and to appl...
    Authors:Bo Qiu, Qi Wen Li, Xin Lei Ai, Bin Wang, Jian Huan, Zheng Fei Zhu, Gen Hua Yu, Ming Ji, Hai Hang Jiang, Cheng Li, Jun Zhang, Li Chen, Jin Yu Guo, Yin Zhou and Hui Liu
    Citation:Radiation Oncology 2020 15:124
    Content type:Research
     
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  32. To review a single institutional experience of the Radiation Therapy Oncology Group (RTOG) 8502 “QUAD shot” regimen using volumetric modulated arc radiotherapy (VMAT) for incurable head and neck cancer (HNC).
    Authors:Ryo Toya, Tetsuo Saito, Kohsei Yamaguchi, Tomohiko Matsuyama, Takahiro Watakabe, Tadashi Matsumoto, Ryoji Yoshida, Akiyuki Hirosue, Daizo Murakami, Yorihisa Orita, Hideki Nakayama and Natsuo Oya
    Citation:Radiation Oncology 2020 15:123
    Content type:Research
     
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  33. Patients with left-sided breast cancer frequently receive deep inspiration breath-hold (DIBH) radiotherapy to reduce the risk of cardiac side effects. The aim of the present study was to analyze intra-breath-h...
    Authors:D. Reitz, F. Walter, S. Schönecker, P. Freislederer, M. Pazos, M. Niyazi, G. Landry, F. Alongi, E. Bölke, C. Matuschek, M. Reiner, C. Belka and S. Corradini
    Citation:Radiation Oncology 2020 15:121
    Content type:Research
     
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  34. To investigate the role of intensity-modulated proton therapy (IMPT) compared to volumetric modulated arc therapy (VMAT), realised with RapidArc and RapidPlan methods (RA_RP) for neoadjuvant radiotherapy in lo...
    Authors:Eren Celik, Wolfgang Baus, Christian Baues, Wolfgang Schröder, Alessandro Clivio, Antonella Fogliata, Marta Scorsetti, Simone Marnitz and Luca Cozzi
    Citation:Radiation Oncology 2020 15:120
    Content type:Research
     
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  35. After esophagectomy, adjuvant chemotherapy (S + CT) and adjuvant chemoradiotherapy (S + CRT) can improve survival in patients with node-positive resectable esophageal cancer. However, we are not aware of any s...
    Authors:Qifeng Wang, Jinyi Lang, Tao Li, Lin Peng, Wei Dai, Yinchun Jiang, Tianpeng Xie, Qiang Fang, Yi Wang, Lei Wu, Bangrong Cao and Yongtao Han
    Citation:Radiation Oncology 2020 15:119
    Content type:Research
     
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  36. Adrenocortical carcinoma (ACC) is a rare and highly aggressive malignancy. Surgical resection is the standard treatment for localized ACC, but the local recurrence remains high. Adjuvant radiation (ART) has be...
    Authors:Jiawei Zhu, Ziye Zheng, Jing Shen, Xin Lian, Zheng Miao, Jie Shen and Fuquan Zhang
    Citation:Radiation Oncology 2020 15:118
    Content type:Research
     
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  37. Patients with left-sided breast cancer have an increased risk of cardiovascular disease (CVD) after radiotherapy (RT). While the awareness of cardiac toxicity has increased enormously over the last decade, the...
    Authors:Aurélie Gaasch, Stephan Schönecker, Cristoforo Simonetto, Markus Eidemüller, Montserrat Pazos, Daniel Reitz, Maya Rottler, Philipp Freislederer, Michael Braun, Rachel Würstlein, Nadia Harbeck, Maximilian Niyazi, Claus Belka and Stefanie Corradini
    Citation:Radiation Oncology 2020 15:117
    Content type:Research
     
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  38. Sarcopenia is defined by a loss of skeletal muscle mass with or without loss of fat mass. Sarcopenia has been associated to reduced tolerance to treatment and worse prognosis in cancer patients, including pati...
    Authors:Romain Mallet, Romain Modzelewski, Justine Lequesne, Sorina Mihailescu, Pierre Decazes, Hugues Auvray, Ahmed Benyoucef, Fréderic Di Fiore, Pierre Vera, Bernard Dubray and Sébastien Thureau
    Citation:Radiation Oncology 2020 15:116
    Content type:Research
     
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  39. Stereotactic radiosurgery (SRS) is an effective treatment for trigeminal neuralgia (TN). Nevertheless, a proportion of patients will experience recurrence and treatment-related sensory disturbances. In order t...
    Authors:Alfredo Conti, Gueliz Acker, Antonio Pontoriero, Juliane Hardt, Anne Kluge, Alberto Cacciola, Giuseppe Iatì, Markus Kufeld, Volker Budach, Peter Vajkoczy, Giancarlo Beltramo, Stefano Pergolizzi, Achille Bergantin, Franziska Loebel, Silvana Parisi, Carolin Senger…
    Citation:Radiation Oncology 2020 15:115
    Content type:Research
     
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  40. We evaluated whether pre- and mid-treatment metabolic tumor volume (MTV) predicts per lesion local recurrence (LR) in patients treated with definitive radiation therapy (RT, dose≥60 Gy) for locally advanced no...
    Authors:Michael S. Binkley, Julie L. Koenig, Mehr Kashyap, Michael Xiang, Yufei Liu, Quaovi Sodji, Peter G. Maxim, Maximilian Diehn, Billy W. Loo Jr and Michael F. Gensheimer
    Citation:Radiation Oncology 2020 15:114
    Content type:Research
     
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  41. The number of nonagenarian cancer patients (≥ 90 years) is continuously increasing, and radiotherapy is performed in a relevant proportion of patients, as surgery and chemotherapy are often not feasible for th...
    Authors:Tanja Sprave, Alexander Rühle, Raluca Stoian, Alina Weber, Constantinos Zamboglou, Carsten Nieder, Anca-Ligia Grosu and Nils H. Nicolay
    Citation:Radiation Oncology 2020 15:113
    Content type:Research
     
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  42. Soft tissue sarcomas (STS) treatment remains a therapeutic challenge. Intraoperative radiotherapy (IORT) resembles a safe and efficient for STS treatment. The first data on electronic-IORT (eIORT) using low-en...
    Authors:Gustavo R. Sarria, Vera Petrova, Frederik Wenz, Yasser Abo-Madyan, Elena Sperk and Frank A. Giordano
    Citation:Radiation Oncology 2020 15:110
    Content type:Research
     
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