Genetics - Jul 18, 2018 Edition

Health News and Information - News Medical

July 18, 2018     Genetics     The latest Genetics news from News Medical

New machine learning framework predicts effects of genetic mutations in ‘dark matter’ regions   A new machine learning framework, dubbed ExPecto, can predict the effects of genetic mutations in the so-called "dark matter" regions of the human genome.

New study identifies inherited genetic variants that raise risk of clonal hematopoiesis   A new study led by researchers at Harvard Medical School and the Harvard T.H. Chan School of Public Health has identified some of the first known inherited genetic variants that significantly raise a person's likelihood of developing clonal hematopoiesis, an age-related white blood cell condition linked with higher risk of certain blood cancers and cardiovascular disease.         Horizontal Gene Transfer and Antibiotic Resistance   The process of horizontal gene transfer (otherwise known as HGT) can be described as one organism acquiring the DNA of another organism.

Single genetic change in gut bacteria can lead to obesity   A new study has shown that a single genetic change in a bacterium of the gut microbiome can lead to metabolic diseases such as obesity.       Study highlights potential of fetal gene therapy to prevent lethal neurodegenerative disease   A fatal neurodegenerative condition known as Gaucher disease can be prevented in mice following fetal gene therapy, finds a new study led by UCL, the KK Women's and Children's Hospital and National University Health System in Singapore.       Study finds genetic heritage to be dominant factor in heart failure   Heart failure is known to be more common in certain families but whether this familial transition is caused by genetic or lifestyle factors.       CRISPR/Cas9 gene editing can cause greater genetic damage than previously thought   Scientists at the Wellcome Sanger Institute have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought. These results create safety implications for gene therapies using CRISPR/Cas9 in the future as the unexpected damage could lead to dangerous changes in some cells.

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