herenciageneticayenfermedad: Biochemistry | Medical News | Medical Articles

miércoles, 18 de septiembre de 2019

Biochemistry | Medical News | Medical Articles | Biochemistry |

	September 18, 2019
	Biochemistry
	The latest biochemistry news from AZoNetwork

Designing Fiber Probes for Real-Time Reaction Monitoring and Biopharmaceutical Analysis

Updated fiber probe design can improved functionality in experimental and industrial applications including biopharmaceutical analysis, real-time reaction monitoring, analytical characterization and the production and development of biofuel. These applications are possible thanks to probe’s specialization of transmission spectroscopy in liquids at long distance in the ranges of UV - VIS and VIS - NIR.

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			Smoking simulator captures synthetic cannabinoid combustion products Researchers have developed a smoking simulator that enables the accurate analysis and reliable detection of the combustion products that are formed when synthetic cannabinoids are smoked.

			Scientists take first step towards digital map of the ion channels in the brain Researchers from école Polytechnique Fédérale de Lausanne, Switzerland (EPFL) have mapped the molecular workings of potassium ion channels within the brain. The study titled, “A kinetic map of the homomeric voltage-gated potassium channel (Kv) family,” was published in the latest issue of the journal Frontiers in Cellular Neuroscience.

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	Eliminating American Foulbrood using Endolysins Honeybees are impacted by several pathogens, including bacteria, fungi, viruses, and other parasites. American Foulbrood is one of the most potent diseases that affects the honeybee larvae of the Apis species and leads to sepsis and death of honeybee larvae.

	Exploring the Structure-Activity Relationship (SAR) of Drugs The structure-activity relationship (SAR) aids in understanding various aspects of drug discovery, from screening drug candidates to optimizing their properties. The effective biological activity is contributed by the various geometric and electrostatic interactions.

	Importance of Solubility and Lipophilicity in Drug Development Solubility and lipophilicity are basic physicochemical properties, but also key parameters that can dictate the success or failure rate of drug discovery and development. In short, their measurement is pivotal for both in vitro and in silico evaluation of drug properties.

	Using Yeast to Produce Novel Cannabinoid Analogs Researchers have successfully recreated the entire biosynthetic pathway for a range of major cannabinoids – including TCH and CBD in the yeast Saccharomyces cerevisiae. Manipulation of gene expression and enzyme promiscuity enabled the team to alter both the flux and activities of several pathways to produce both standard cannabinoids and rare analogs.

	Removal of a critical enzyme may help cases of sepsis finds research Scientists at the University of California San Diego School of Medicine have shown that removal of an enzyme called the PH domain Leucine-rich repeat Protein Phosphatase 1 (PHLPP1) could help laboratory mice with sepsis in a model they had created for their experiment. The study titled, “PHLPP1 counter-regulates STAT1-mediated inflammatory signalling,” was published this week in the journal eLife.