Malaria - Infectious Diseases PHGKB -

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Malaria

- Infectious Diseases PHGKB -

What's New

Last Posted: Sep 26, 2019

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• A histone methyltransferase inhibitor can reverse epigenetically acquired drug resistance in the malaria parasite Plasmodium falciparum 
  Chan A, et al. bioRxiv, Sep 19, 2019.
• Rare mutations in Pfmdr1 gene of Plasmodium falciparum detected in clinical isolates from patients treated with anti-malarial drug in Nigeria. 
  Idowu Abel O et al. Malaria journal 2019 Sep (1) 319
• Targeted Next Generation Sequencing for malaria research in Africa: current status and outlook. 
  Ghansah Anita et al. Malaria journal 2019 Sep (1) 324
• Deployment and utilization of next-generation sequencing of Plasmodium falciparum to guide anti-malarial drug policy decisions in sub-Saharan Africa: opportunities and challenges. 
  Ishengoma Deus S et al. Malaria journal 2019 Sep (1) 267
• The ferroportin Q248H mutation protects from anemia, but not malaria or bacteremia. 
  Muriuki John Muthii et al. Science advances 2019 Sep (9) eaaw0109
• An improved nucleic acid extraction method from dried blood spots for amplification of Plasmodium falciparum kelch13 for detection of artemisinin resistance. 
  Zainabadi Kayvan et al. Malaria journal 2019 Jun (1) 192
• A roadmap for malaria research. 
  Winzeler Elizabeth A et al. Science (New York, N.Y.) 2019 Aug (6455) 753-754
• Genomic analysis informs malaria evolution. 
  Sibley Carol Hopkins et al. Science (New York, N.Y.) 2019 Aug (6455) 752-753
• The Malaria Cell Atlas: Single parasite transcriptomes across the complete Plasmodium life cycle. 
  Howick Virginia M et al. Science (New York, N.Y.) 2019 Aug (6455)
• Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study. 
  van der Pluijm Rob W et al. The Lancet. Infectious diseases 2019 Jul